Allied Bioscience, Inc.

Srfc Bio, Inc.

Misagh Alipour

Craig Grossman

Gavri Grossman

Jie Fang

Daniel A Moros

Daniel Moros

The present disclosure provides antimicrobial coating compositions that are used to form residual antimicrobial coatings on medical implements and medical devices including the components of medical equipment such as CPAP/BiPAP machines. Antimicrobial coating compositions comprise at least one of an organosilane (RO)Si&#x2014;R&#x2014;Z, an organic amine RRRN, a titanium (IV) species, a 1,2-diol, an &#x3b1;-hydroxy acid, a &#x3b2;-hydroxy acid, and an organosilane grafted parylene polymer, wherein Ris H, alkyl, substituted alkyl, aryl or substituted aryl, Ris a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent, and R, R, and Rare independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

Antimicrobial coatings for medical implements and medical devices

A wet wipe is disclosed that provides both contact sanitization of a surface and application of a residual antimicrobial coating on the surface through the same wiping. The wet wipe comprises a substrate such as an absorbent nonwoven fabric and a liquid composition impregnated therein, the liquid composition comprising an organosilane such as the antimicrobial dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride, a non-silane quaternary disinfectant, an organic amine, and a solvent. The non-silane quaternary actives comprise a mixture of actives, and the solvent comprises 60 wt. % isopropanol or more.

Wet wipes comprising antimicrobial coating compositions

The present disclosure provides antimicrobial coating compositions that are used to form residual antimicrobial coatings on medical implements and medical devices including the components of medical equipment such as CPAP/BiPAP machines. Antimicrobial coating compositions comprise at least one of an organosilane (RO)Si&#x2014;R&#x2014;Z, an organic amine RRRN, a titanium (IV) species, a 1,2-diol, an &#x3b1;-hydroxy acid, &#x3b2;-hydroxy acid, and an organosilane grafted parylene polymer, wherein Ris H, alkyl, substituted alkyl, aryl or substituted aryl, Ris a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent, and R, R, and Rare independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

Antimicrobial coating compositions are used to form dried residual antimicrobial coatings on medical dressings including gauze, bandages, gowns and dry wipers. Antimicrobial coating compositions comprise at least one of an organosilane (RO)Si&#x2014;R&#x2014;Z, an organic amine RRRN a titanium (IV) species, a 1,2-diol, an &#x3b1;-hydroxy acid, a &#x3b2;-hydroxy acid, and an organosilane grafted parylene polymer, wherein Ris H, alkyl, substituted alkyl, aryl or substituted aryl, Ris a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent and R, R, and Rare independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

Growing community of inventors

Surrey, Canada

Misagh Alipour