Astrazeneca Ab

Neomed Institute

Other

Bellus Health Cough Inc.

Miroslaw Jerzy Tomaszewski

Xuehong Luo

Louis-David Cantin

Yun-Xing Cheng

Yun-Jin Hu

Christophe Buon

Carmen Leung

Simon Woo

Vijayaratnam Santhakumar

Christopher Walpole

Hua Yang

Mehrnaz Pourashraf

This invention generally relates to substituted imidazopyridine compounds, particularly substituted 4-(imidazo[1,2-a]pyridin-2-yl)benzamide compounds and salts thereof. This invention also relates to pharmaceutical compositions and kits comprising such a compound, uses of such a compound (including, for example, treatment methods and medicament preparations), processes for making such a compound, and intermediates used in such processes.

Imidazopyridine compounds and uses thereof

This invention generally relates to substituted imidazopyridine compounds, particularly substituted 4-(imidazo[1,2-a]pyridin-2-yl)benzamide compounds and salts thereof. This invention also relates to pharmaceutical compositions and kits comprising such a compound, uses of such a compound (including, for example, treatment methods and medicament preparations), processesor making such a compound, and intermediates used in such processes.

This invention generally relates to substituted benzoimidazole compounds, particularly methyl 2-((2-(2,6-difluoro-4-(methylcarbamoyl)phenyl)-5-methyl-1H-benzo[d]imidazol-1-yl)methyl)morpholine-4-carboxylate and salts thereof. This invention also relates to pharmaceutical compositions and kits comprising such a compound, uses of such a compound (including, for example, treatment methods and medicament preparations), processes for making such a compound, and intermediates used in such processes.

Benzoimidazole compounds and uses thereof

Compounds of Formula I, or pharmaceutically acceptable salts thereof: wherein R, R, X, m and n are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

Piperidine derivatives and their use as muscarinic receptor modulators

Compounds of Formulae I, or pharmaceutically acceptable salts thereof: wherein A, A, G, GG, R, R, X, Y, Z, m, n and p are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

Compounds

The present invention relates to new compounds of formula I, 

Compounds of Formula (I) wherein R, R, R, Rand X are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain 

Benzodiazepine derivatives, preparation thereof and use thereof

Compounds of general formula (I), are disclosed and claimed in the present application, as well as salts and pharmaceutical compositions comprising the novel compounds and their use in therapy, in particular in the management of pain

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Montreal, Canada

Miroslaw Jerzy Tomaszewski