Hoffmann-la Roche Inc.

Roche Diagnostics Operations, Inc.

Ventana Medical Systems, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Prothena Biosciences Limited

Mirko Ritter

Kay-Gunnar Stubenrauch

Elke Faatz

Uwe Wessels

Rudolf Vogel

Peter Muench

Frank Kowalewsky

Astrid Reiser

Markus Zadak

Lidija Pestic-Dragovich

Tsu-Shuen Tsao

Lei Tang

Styliani Tournaviti

Ronald Torres

Adriana Racolta

Wagner Marcelo Zago

Thomas Kremer

Sebastian Dziadek

Christian Czech

Marta Canamero

Janis Brockhaus

Gloria Tabares

Methods and compositions for accurate identification of Parkinson's disease are disclosed. More particularly, the disclosure is directed to the determination of Parkinson's disease in ante-mortem tissue samples.

Determination of Parkinson's disease

The invention provides anti-variant Fc-region antibodies which specifically bind to an antibody that has the mutation P329G or the mutations P329G/L234A/L235A or the mutations 1253A/H310A/H435A in the Fc-region, and methods of using the same.

Anti-variant Fc-region antibodies and method of use

Herein is reported a cultivation system for cultivating a pool of ovine B-cells or single deposited ovine B-cells in the presence of phorbol myristate acetate (PMA).

Method for producing antibodies using ovine B-cells and uses thereof

The present invention relates to in vitro methods for determining the presence or absence of an anti-drug antibody (ADA) or drug/ADA immunecomplexes in a minipig sample. The invention further relates to antibodies specifically binding to minipig IgG that are applicable in the methods of the invention.

Method for determining anti-drug antibodies in a minipig sample

The invention provides anti-variant Fc-region antibodies which specifically bind to an antibody that has the mutation P329G or the mutations P329G/L234A/L235A or the mutations I253A/H310A/H435A in the Fc-region, and methods of using the same.

Growing community of inventors

Bernried, Germany

Mirko Ritter