Centre National De La Recherche Scientifique

Université Pierre Et Marie Curie (Paris 6)

Université De Bretagne Occidentale

Centre Hospitalier Universitaire De Brest

Université Pierre Et Marie Curie

Mirjam Czjzek

Gurvan Michel

Philippe Potin

William Helbert

Tristan Barbeyron

Christian Berthou

Ludovic Delage

Bertrand Cosson

Hussam Saad

Patrick Cormier

Catherine Leblanc

Etienne Rebuffet

Jan-Hendrik Hehemann

Gaëlle Correc

Gaeelle Correc

The invention relates to the A1 peptide of the sequence RRKYGRDFLLRF, as well as to certain variants thereof, for treating cancers, in particular malignant hematopoietic diseases, and more particularly for treating chronic lymphoid leukaemia.

Peptides used for treating cancers and, in particular, chronic lymphoid leukaemia

The present invention concerns iodoperoxidases from, isolated nucleic acids encoding same, as well as methods for preparing these enzymes. Moreover, the invention is also directed to the use of such iodoperoxidases in a wide range of industrial, pharmaceutical, medical, cosmetics, and ecological applications, as well as in the food industry.

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The present invention relates to the isolation and to the characterization of two proteins having a novel enzymatic activity, i.e. a porphyranase activity. These proteins are useful for hydrolyzing polysaccharides containing sulfated agaro-colloids and for producing oligo-porphyrans, notably oligo-porphyrans with a defined structure and size.

Porphyranases, and use thereof for hydrolyzing polysaccharides

Growing community of inventors

Plougoulm, France

Mirjam Czjzek