Galapagos Nv

Miriam López Ramos

Steven Emiel Van Der Plas

Reginald Christophe Xavier Brys

Xavier Marie Bock

Oscar Mammoliti

David Amantini

Agnès Marie Joncour

Pieter Isabelle Roger Claes

Denis Maurice Annoot

Sébastien Laurent Xavier Martina

Frédéric Gilbert Labéguère

Ghjuvanni Petru Diunisu Coti

Taoues Temal-laïb

René Alexandre Galien

Réginald Christophe Xavier Brys

Stéphane Nicolas Alain Beaumont

Daniel Comas Martinez

The present invention discloses compounds according to Formula I: The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of allergic diseases, inflammatory diseases, metabolic diseases, autoinflammatory diseases, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IFNα, IL12 and/or IL23 by administering the compound of the invention.

Compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders

The present invention discloses compounds according to Formula I: Wherein R, L, R, L, R, Cy, and the subscript n are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of allergic diseases, inflammatory diseases, metabolic diseases, autoinflammatory diseases, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IFN&#x3b1;, IL12 and/or IL23 by administering the compound of the invention.

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Romainville, France

Miriam López Ramos