Rhone-poulenc Chimie

Rhodia Chimie

Mireille Labrouillere

Jean-Roger Desmurs

Jacques Dubac

Christophe Le Roux

Andre Laporterie

Andr&eacute; Laporterie

Hafida Gaspard

A method for acylating an aromatic compound, specifically an activated or deactivated aromatic compound, is disclosed. The method is suitable for preparing aromatic ketones. The preparation of a catalyst and novel bismuth compounds is also disclosed. Said aromatic compound acylation method comprises reacting said aromatic compound with an acylating agent in the presence of a catalyst, and is characterised in that the acylation reaction is performed in the presence of an effective amount of at least one bismuth salt of trifluoromethanesulphonic acid.

Aromatic compound acylation method

Aromatic ethers/phenols are acylated, characteristically into hydroxy- and/or alkoxyaromatic alkylketones, and in particular, are acylated in the para-position relative to an alkoxy substituent borne by the aromatic nucleus, by reacting/condensing same with an acylation agent, for example acetyl chloride or acetic anhydride, in the presence of a catalytically effective amount of a bismuth halide, or a precursor compound that generates, in situ, a bismuth halide.

Acylation of aromatic ethers/phenols

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Agen, France

Mireille Labrouillere