Warner-lambert Company

Université Du Québec À Montréal

Histapharm Inc.

B-organic Films Corp.

Karici Diagnostics Inc.

Matripharm Inc.

Mircea-Alexandru Mateescu

Joanne Paquin

Le Tien Canh

Tien Canh Le

Pompilia Ispas-Szabo

Rodolfo Federico

Éric De Grandpré

Bruno Mondovi

Carmen Calinescu

&Eacute;ric De Grandpr&eacute;

Mihaela Friciu

Canh Le Tien

The present document describes a powder composition comprising a functionalized starch having a single helix V-structure and having a degree of substitution of at least 0.25, and a bioactive agent, forming an inclusion complex with said functionalized starch, where the bioactive agent is within the helix V-structure of the functionalized starch having a single helix V-structure. Also described are the functionalized starch having a single helix V-structure and having a degree of substitution of at least 0.25, methods of making the same and methods of using the same to manufacture the powder composition.

Bioactive agents included in functionalized starch having a single helix V-structure

The present disclosure describes compositions for intestinal delivery of enzyme formulations and methods of treating health problems with these formulations. More specifically, the enzyme formulations include at least one histaminase and various methods of treatment of physical conditions, such as inflammation, allergy, histamine intolerance, and intestinal cancer.

Oral enzyme compositions for intestinal delivery

A neuroprotective composition for protecting neuronal cells against oxidative stress and methods for using and preparing the same. More particularly, the neuroprotective composition of the invention comprises a mixture of pyruvate, antioxidant, and lipid(s) such as fatty acids. The neuroprotective composition could be used for the treatment of brain trauma, brain or cerebrovascular ischemia, neurodegenerative diseases, poisoning of neuronal cells, the diminution of drugs side effects and for preservation of neuronal grafts.

Neuroprotective composition and uses thereof

A neuroprotective composition for protecting neuronal cells against oxidative stress and methods for using and preparing the same. More particularly, the neuroprotective composition of the invention comprises a therapeutically effective amount of ceruloplasmin or a functional derivative thereof. The neuroprotective composition is characterized in that it protects neuronal cells from reactive oxygen species such as &bull;O and &bull;OH. In a preferred embodiment, the neuroprotective composition further comprises an antioxidant consisting of catalase or of an amphiphilic physiological antioxidative solution comprising a mixture of pyruvate, antioxidant, and lipid(s) such as fatty acids. The neuroprotective composition could be used for the treatment of brain trauma, brain or cerebrovascular ischemia, neurodegenerative diseases, poisoning of neuronal cells, the diminution of drugs side effects and for preservation of neuronal grafts.

Ceruloplasmin and an antioxidant composition comprising the same and their uses as neuroprotective agent

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Montréal, Canada

Mircea-Alexandru Mateescu