Namiki Seimitsu Houseki Kabushiki Kaisha

Honda Giken Kogyo Kabushiki Kaisha

Honda Motor Co., Ltd.

Sumitomo Electric Industries, Limited

The Ohtsu Tire & Rubber Co., Ltd.

Quarrymen&co. Inc.

Namiki Seimitsu Hoseki Kabushiki Kaisha

Namiki Precision Jewel Co., Ltd.

Namiki Seimitsu Houseki Kabushiki

Namiki Seimitsu Houseki

Namika Precision Jewel Co., Ltd.

Keihin Corporation

Namiki Seimitu Houseki Kabushiki Kaisha

Minoru Ueda

Shoichi Kaneda

Kenji Ueno

Takayuki Kumagai

Teruo Yoshinari

Hiroshi Yamashita

Tsuneo Kyono

Yoshihiro Takada

Yuji Tsushima

Yutaka Nishikawa

Fumio Fujimori

Hiroshi Tanaka

Michitomo Iiyama

Masaki Ueno

Toshio Suzuki

Satoshi Takeuchi

Kazuhito Hotta

Mitsuo Nakagawa

Hiroshi Yoshida

Katsuichi Yagisawa

Toichiro Hikichi

Hiroshi Yamada

Akira Hayashi

Yuuichi Hashimoto

Toshiyuki Kubota

Shiro Kokubu

Fumio Funjimori

Yasuaki Nagai

Naoki Tsushima

Kenichiro Ikeda

Shunji Akamatsu

Katsuhiko Fujii

Toshikazu Saito

Tsuyoshi Takano

Hiroshi Kimoto

Katsunori Komuro

Fumie Okada

Tsuneo Kyouno

Hideaki Andoh

Masami Mitsuhashi

Yoshihide Namba

Nobuo Mashino

Hiroshi Minekawa

Eisaku Andou

Yasushi Tokoyo

Etsuo Ohno

Etuo Oono

Kazuyuki Yoshida

Toshihiro Arai

Toshihiko Naito

Michiru Fukuda

Mineo Torikai

Motohiro Mishima

Shinichiro Yazawa

Junichi c/o Kakuda Development Center Keihin Corporation Shimokawa

Hiroshige c/o Kakuda Development Center Of Keihin Corporation Akiyama

The invention provides a novel anticancer therapeutic having a high effect against solid cancers, lacking the side effects of chemotherapeutics, and being unlikely to cause resistance. Provided is a pharmaceutical composition for cancer treatment prepared by a method having: a stem cell production step for making immortalized stem cells by introducing four types of genes into deciduous tooth dental pulp stem cells obtained from the dental pulp of mammals; and a condition medium preparation step for culturing the immortalized stem cells for a predetermined length of time in serum-free medium at 23-27&#xb0; C. under conditions of low oxygen concentration at an oxygen concentration of from 0.5% to less than 20%, the pharmaceutical composition containing 1.5 times or more of insulin-like growth factor (IGF-1) and vascular endothelial growth factor (VEGF) than is contained in condition medium prepared when culturing at an oxygen concentration of 20% and otherwise identical conditions.

Method of making conditioned medium from immortalized dental pulp stem cells

The purpose of the present invention is to provide immortalized stem cells, which produce a growth factor capable of regenerating various kinds of tissues that have been damaged by a variety of causes, and a method for producing the aforesaid immortalized stem cells. Another purpose is to provide a medicinal composition and a medicinal preparation for restoring damaged tissues, and a method for the percutaneous absorption of a culture supernatant. Provided are immortalized stem cells that are obtained by isolating stem cells selected from the group consisting of mammalian mesenchymal cells, an embryo at the early stage of the development and somatic cells, first culturing the cells to give first stage culture cells, transferring four kinds of genes into the first stage culture cells to give transgenic cells, and selecting the desired immortalized stem cells from among the transgenic cells using the expression of STRO-1 as an index.

Immortalized stem cell, compositions, preparations and uses thereof

[Problems] To provide a multifunction vibration actuator which has flat rising and falling frequency characteristic at the time of generation of bodily sensation vibration and which is stable for an input signal. [Means for Solving Problems] Flat frequency characteristics can be obtained by using a two-fold rotational symmetry frame type suspension, and miniaturization of the whole multifunction vibration actuator can be made by the user of the frame type suspension. With regard to the frame type suspension, use of protruded configuration of corner parts ensures the effect of absorption of deflection of the suspension.

Suspension structure

A multifunction oscillatory actuator which performs acoustic reproduction by an acoustic reproduction section includes a diaphragm having a voice coil attached thereto and performs the occurrence of somesthetic oscillation by a magnetic circuit section having a magnet attached thereto, and in which the acoustic reproduction section and the magnetic circuit section are attached to a housing having a cylindrical shape, such that the magnetic circuit section is supported on an inner wall of the housing by a frame-shaped suspension.

Multi-function vibration actuator

A magnetic circuit including a pole piece, a magnet, and a yoke is supported by using a suspension where outer and inner circumferential portions thereof are connected to each other with a supporting member, and the outer circumferential portion of the suspension is fixed to protrude from a housing or an inner wall of a cover provided with a stepped portion in a direction passing over the magnetic circuit toward an inner portion, so that it is possible to limit a movable range of the magnetic circuit by using the outer circumferential portion of the suspension and to prevent inner components of a main body of the multi-function vibration actuator from being destructed at the time of being impacted due to falling.

Secondary fuel filter () provided downstream of a fuel pump () has a smaller pore size than a primary fuel filter () provided upstream of the fuel pump. The secondary fuel filter is covered with a case member () and positioned along a center frame () of the vehicle. The secondary fuel filter is made of non-woven fabric and formed in a bag shape, and fuel is filtered by the secondary fuel filter as it passes from the interior to the outside of the filter.

Vehicle fuel supply device and fuel filter structure

A contact terminal which prevents a load from being concentrated on the contact terminal portion thereof when a part is disposed on a substrate, to prevent contact terminals from being short-circuited even if stacked, thereby reducing the overall space requirement. A projection is formed on a terminal base and the movable range of a contact is limited by the projection, whereby the load that is conventionally concentrated on a terminal support part can be distributed by a support part and the projection. Consequently, the durability of the terminal portion can be enhanced, the space for the contact terminal portion is saved, and a short circuit is prevented from occurring due to the contacting between the contact terminals.

Power supply terminal structure

A magnetic circuit unit includes a pole piece, a magnet, and a yoke and a suspension made of a magnetic material. A magnetic gap is formed between an inner circumferential side surface of the suspension and a circumference of the pole piece. Accordingly, it is possible to allow the magnet in the magnetic circuit unit to be thinly constructed. In addition, it is possible to implement a multi-function vibration actuator having a thin structure and capable of obtaining a sufficiently sensible vibration.

Thin multi-function vibration actuator

This invention realizes an incoming call notification operation for portable equipments in which the amplitude of vibration matches the rhythm of the melody, by electrically connecting an electromagnetic induction actuator that produces melody and vibration to an integrated circuit that outputs the melody generation signal and the vibration signal, and by applying to the electromagnetic induction actuator either the melody generation signal from the integrated circuit or a signal created by mixing the melody generation signal and the vibration generation signal.

Arrival alerting device, arrival alerting method, and mobile terminal

A workpiece transfer system includes a bracket rotatably supported on a support part, a rotary drive mechanism provided on the support part in order to rotate the bracket, a workpiece support arm swingably and axially supported on the bracket, a swing drive mechanism provided on the bracket in order to swing the workpiece support arm, and a workpiece retainer provided on a tip end part of the workpiece support arm and retaining a workpiece that is to be transferred, the workpiece being inclined by operation of the swing drive mechanism when the rotary drive mechanism is operated so that a center of gravity of the workpiece comes on the vicinity of an axis of rotation of the rotary drive mechanism. This reduces the rotational load on the rotary drive mechanism, and since a small size and a reduction in weight can be achieved for the system, the workpiece transfer system and method enables a single worker to easily give a workpiece an inclination and inversion attitude change.

Workpiece transfer system and workpiece transfer method

To enable the mounting of a multifunctional vibrating actuator on the surface of a circuit board by solder reflow without exposing the components with poor heat resistance the diaphragm, magnet, and voice coil&#x2014;to the high temperatures of the reflow tank, the structure for mounting a multifunctional vibrating actuator on a circuit board is constituted such that a bracket is fixed to the surface of the circuit board by solder reflow, and then the housing of the multifunctional vibrating actuator is placed in the bracket so that the terminals of the multifunctional vibrating actuator are electrically connected to the electrodes of the circuit board.

Structure for mounting multifunctional vibrating actuator on circuit board

The present invention is a multifunctional actuator including a magnetic circuit, a suspension that supports the magnetic circuit, a diaphragm positioned facing the magnetic circuit, and a voice coil that is mounted on the diaphragm and inserted in a circular air gap of the magnetic circuit, comprising a housing to accommodate the magnetic circuit, and a cover to cover an open end of the housing, wherein a sound release gap is formed between an outer periphery of the housing and a side wall of the cover for communication between the inside and outside of said housing. Thereby, it can prevent the infiltration of foreign matter into the housing without attaching a dust mesh or non-woven fabric over the sound release hole.

Multifunctional actuator and mobile terminal

To accurately tune the vibration frequency of a suspension during assembly. Secured positionswhere a magnetic circuit partis secured to a suspensionare provided near to each other. From among the secured positions, secured positionssuitable for the characteristics of a suspensionto be mounted and the weight of a magnetic circuit partare selected and secured to each other. Thus, the distance between the securing position and the central position of vibration of a suspensionand a housingcan be changed to tune the frequency to the desired value.

Multifunction-type vibration actuator and mobile terminal device

A multifunction-type vibration actuator and a mobile terminal device capable of decreasing the lowest acoustic resonance frequency and preventing breakage of a coil lead as well as improving acoustic characteristics and preventing sound leaks. A portion near the outer periphery of a diaphragmis bent to form a rising portionextending along an inner peripheryof a housingtoward an open end thereof. This rising portionserves as a corrugation to decrease the lowest resonance frequency and the amplitude of vibration of which a fulcrum is served by the rising portionis not so large as that of the corrugation. Accordingly, the coil lead of a voice coilis not easily broken. Furthermore, an extending portionis formed to extend outward along a flat surfaceformed at the open end of a housingfrom a rising portion. This enlarges the entire radius of the diaphragmand improves the acoustic characteristics. Moreover, by arranging a flat surfaceof a housingparallel to an extending portionof a diaphragm, a gasket can easily be attached.

A multifunction vibration actuator is disclosed, which includes a housing () integrally formed with a first house part () with an elliptic wall (), a second house part () having a cylindrical wall () with a diameter corresponding to the first house part () at the center of the ellipse, and both bottom walls () and () of the first housing part (). The actuator also includes an elliptic diaphragm () with an annular voice coil () installed on the inner surface thereof, a circular magnetic circuit part (), and a disk type suspension (). The elliptic diaphragm () is tightly installed in the wall of the first house part (), and the circular magnetic circuit part () is installed in the cylinder of the second house part () with the suspension ().

Multifunction-type vibration actuator and portable communication equipment

Growing community of inventors

Tokyo, Japan

Minoru Ueda