Other

Sekisui Chemical Co., Ltd.

Minoru Seki

Mitsutoshi Nakajima

Kazuki Yamamoto

Hiroshi Nabetani

Hiroji Fukui

Yuji Kikuchi

Yoshinori Akagi

Sosaku Ichikawa

Junya Takagi

Tatsuo Maruyama

Jihong Tong

Shinji Sugiura

A microfluidic device provided with a micro-channel structure capable of easily and positively providing therein micro-droplet having various dilution ratios. A micro-channel structure provided in a substrate () has a first mixing unit () and a second mixing unit () connected to the downstream side of the first mixing unit (), with each mixing unit () having first through third micro-channels. One end of a first weighing unit () consisting of a micro-channel having a capacity equivalent to the volume of a specified-amount first micro-droplet is opened to a first micro-channel (), and the other end is opened to a merging unit () provided on a second micro-channel (). One end of a second weighing unit () consisting of a micro-channel having a capacity equivalent to the volume of a specified-amount second micro-droplet is connected to a third micro-channel (), and the other end is opened to the merging unit (). Any one of the first through third outlet ports of the first mixing unit is connected with the first or the third inlet port of the second mixing unit ().

Micro fluid device and trace liquid diluting method

This invention provides a measuring apparatus for microanalysis, which can be simply manufactured and can realize a number of analyses and measurements in a small analyte amount and particularly can analyze and measure a number of analytes having different concentrations and different analytes in a simultaneous and easy manner, and a measurement method of microanalysis using the apparatus. The measuring apparatus for microanalysis is characterized by comprising detection parts of m lines and n rows in communication with a micropassage for a waste solution, chambers of m lines and n rows in communication with the respective detection parts through a mixing flow passage, n first micropassages in communication with the respective line chambers through a passive valve, m second micropassages in communication with respective row chambers through a passive valve, and third micropassages in communication with the respective chambers for supplying gas and/or a washing solution.

Microanalysis measuring apparatus and microanalysis measuring method using the same

A method is disclosed for activating a lipase by adding a solution of lipase in an aqueous buffer at a pH near neutrality to an organic phase, e.g., tetradecane. Under these conditions lipase is activated as a function of an organic-and-water boundary surface between the organic and water phases. The lipase that is activated in this manner remains active even after lyophilization to remove the water and the organic phase. This activated lipase efficiently catalyzes a fat reforming reaction in non-aqueous and nano-aqueous conditions.

Method of producing activated lipase

A method to efficiently and continuously produce microspheres of natural oils and fats having a high melting point, the average particle diameter of which is in dozens of &mgr;m and is uniform, comprising the steps of heating oils and fats having a high melting point to a temperature greater than the melting point thereof to liquify same holding the oils and fats in a liquid state, forming a dispersed phase of the liquid oils and fats, pressurizing the dispersed phase and forming emulsions by dispersing the dispersed phase into a continuous phase via a plurality of microchannels, and isolating microspheres of the oils and fats having a high melting point by removing the continuous phase from the emulsions.

Method of producing solid fatty microspheres

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Tokyo, Japan

Minoru Seki