Other

The Green Cross Corporation

Yoshitomi Pharmaceutical Industries, Ltd.

Chisei Ra

Minoru Hirama

Ko Okumura

Koji Naito

Yukiyoshi Yanagihara

Disclosed is an antiallergic composition comprising, as an active ingredient, a peptide which is capable of binding to human IgE, more specifically the high-affinity immunoglobulin E receptor .alpha. chain or a soluble fragment, which is capable of binding to human IgE, or the high-affinity immunoglobulin E receptor .alpha. chain. The composition is clinically useful for blocking allergic responses.

Antiallergic compostion

Disclosed is an antiallergic composition comprising, as an active ingredient, a peptide which is capable of binding to human IgE, more specifically the high-affinity immunoglobulin E receptor .alpha.-chain or a soluble fragment, which is capable of binding to human IgE, or the high-affinity immunoglobulin E receptor .alpha.-chain. The composition is clinically useful for blocking allergic responses. An animal model for use in the screening of prophylactic and therapeutic compositions for IgE-related diseases is also disclosed.

Immunoglobulin E receptor .alpha.-chain inhibits IgE production and

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Osaka, Japan

Minoru Hirama