Harvard College

Mingjie Dai

Peng Yin

Xi Chen

Ralf Jungmann

Feng Xuan

Cameron Myhrvold

Diming Wei

Maier S Avendano Amado

Johannes Benedikt Woehrstein

Yonggang Ke

Maier Avendano

Johannes B Woehrstein

The present disclosure provides, in some embodiments, methods and compositions for single-molecule detection.

Conditional primer extension for single-molecule detection

The present disclosure provides, inter alia, methods and compositions (e.g., conjugates) for imaging, at high spatial resolution, targets of interest.

Quantitative DNA-based imaging and super-resolution imaging

This disclosure provides methods for generating super-resolution patterns of molecules on substrates.

Methods and compositions relating to super-resolution imaging and modification

The invention provides SST motifs of controlled size and shape, comprised of a plurality of oligonucleotides, and methods for their synthesis. The motifs are formed, at least in part, by the self-assembly of single stranded oligonucleotides into curved, corrugated or twisted structures. The location of each oligonucleotide in the resultant motif is known. Accordingly, the motifs may be modified with specificity.

Compositions and methods relating to complex nucleic acid nanostructures

Growing community of inventors

Boston, MA, United States of America

Mingjie Dai