Arkion Life Sciences, LLC

Algenol Biotech LLC

Azitra Inc

Arkion Life Sciences LLC D/b/a/ Bio-technical Resources Division

Ming-De Deng

Alan D Grund

Reinhardt Rosson

J David Angerer

Thomas A Jerrell, Jr

Candice Leanna

Owen Mathre

Jeff Running

Dave Severson

Linsheng Song

Sarah Wassink

Don Cyron

Paul Gordon Roessler

Heike Enke

David R Dodds

Ulf Dühring

Travis Michael Whitfill

Kui Wang

Frank Uliczka

Thomas A Jerrell

Fernando Sanchez-Riera

Kimberly Lynn Anderson

Alexander Tikhonov

Charles Ryan Budinoff

Songhua Zhu

Christian Weissert

Frank Jochem

Jr Thomas A Jerrell

The present disclosure provides recombinantbacterium (e.g.) that are dependent on D-alanine for growth. In one aspect, the disclosure features a recombinantbacterium comprising two inactivated alanine racemase genes (&#x394;alr1&#x394;alr2); and an inactivated D-alanine aminotransferase (dat) gene. In another aspect, the disclosure features a method of making the recombinantbacterium.

Auxotrophic strains ofbacterium

Methods for increasing the genetic stability of genetically enhanced microbial host cells capable of producing a compound of interest are disclosed.

Methods for increasing the stability of production of compounds in microbial host cells

The invention provides genetically modified cyanobacterial cells that are capable of utilizing phosphite as a primary phosphorus source, and can out-compete contaminant organisms for certain forms of phosphorus more effectively.

Cyanobacterial strains capable of utilizing phosphite

A biosynthetic method for producing glucosamine and N-acetylglucosamine is disclosed. Such a method includes the fermentation of a genetically modified microorganism to produce glucosamine and/or N-acetylglucosamine. Also disclosed are genetically modified microorganisms that are useful for producing glucosamine and N-acetylglucosamine. In addition, methods of recovering N-acetylglucosamine that has been produced by a fermentation process, including methods that result in N-acetylglucosamine of high purity, are described. Also disclosed is a method to produce glucosamine from N-acetylglucosamine.

Process and materials for production of glucosamine and N-acetylglucosamine

The present invention provides an isolated linoleate isomerase and its nucleic acid and amino acid sequence. The present invention also provides a method for producing CLA from an oil using an immobilized bacterial cell or an isolated linoleate isomerase.

Linoleate isomerase

The present invention provides an isolated (trans,cis)-10,12-linoleate isomerase and its nucleic acid and amino acid sequences. The present invention also provides a method for producing conjugated linoleic acid or conjugated linolenic acid (CLA), or derivatives thereof, from an oil using an immobilized cell and/or an isolated linoleate isomerase. The present invention also provides an isolated lipase-like protein and its nucleic acid and amino acid sequences. The present invention also provides an isolated acetyltransferase-like enzyme and its nucleic acid and amino acid sequences.

Polynucleotide encoding a propionibacterium linoleate isomerase and uses thereof

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Manitowoc, WI, United States of America

Ming-De Deng