University of California

Berkeley Lights, Inc.

Ming-Chiang Wu

Gaetan L Mathieu

Mark P White

Jian Gong

Randall D Lowe, Jr

Justin K Valley

Jui-Che Tsai

Pei-Yu E Chiou

Tatsuo Itoh

Kevin T Chapman

Shao Ning Pei

Jodi Tsu-An Loo

Aaron T Ohta

Jason M Mcewen

Hsan-Yin Hsu

Arash Jamshidi

Steven L Neale

Single-sided optoelectrowetting (SSOEW)-configured substrates are provided, as well as microfluidic devices that include such substrates. The substrates can include a planar electrode, a photoconductive (or photosensitive) layer, a dielectric layer (single-layer or composite), a mesh electrode, and a hydrophobic coating. Fluid droplets can be moved across the hydrophobic coating of such substrates in a light-actuated manner, upon the application of a suitable AC voltage potential across the substrate and the focusing of light into the photoconductive layer of the substrate in a location proximal to the droplets. Walls can be disposed upon the substrates to form the microfluidic devices. Together the walls and substrate can form a microfluidic circuit, through which droplets can be moved.

Single-sided light-actuated microfluidic device with integrated mesh ground

Described herein are single-sided lateral-field optoelectronic tweezers (LOET) devices which use photosensitive electrode arrays to create optically-induced dielectrophoretic forces in an electric field that is parallel to the plane of the device. In addition, phototransistor-based optoelectronic tweezers (PhOET) devices are described that allow for optoelectronic tweezers (OET) operation in high-conductivity physiological buffer and cell culture media.

Single-sided lateral-field and phototransistor-based optoelectronic tweezers

A system and method of optically routing wavelength channels from within a plurality of optical inputs to any of a plurality of optical outputs. An optical wavelength-selective cross connect (WSXC) switch is described with a first stage of wavelength division multiplexing (WDM) routers which support an optical input and a plurality of optical outputs, which are interconnected to a second stage of WDM routers having a plurality of optical inputs and an optical output. The wavelength channel is routed in two stages from one of the input stage routers to an output stage router for output. It should be appreciated that the WSXC switch of the invention can be utilized for passing optical signals in either direction. In a preferred implementation integrated circuit router chips are stacked into cubes to form the routers stages which are cross coupled using a twisted butt joint to form a WSXC switch.

Compact wavelength-selective optical crossconnect

A 1&#xd7;Nwavelength selective switch (WSS) configuration in which switch elements are configured in a way that enables the input or output fibers to be arranged in a two-dimensional (2D) array. By employing 2D arrays of input/output channels, the channel count is increased from N to Nfor wavelength selective switches. In one embodiment, in which the components are arranged as a 2- &#x192; imaging system, a one-dimensional (1D) array of mirrors is configured such that each mirror has a dual scanning axis (i.e., each mirror can be scanned in X and Y directions). In another embodiment, in which the components are arranged as a 4- &#x192; imaging system, two 1D arrays of mirrors are configured with orthogonal scanning directions. In both embodiments, the number of ports is increased from N to N.

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A 1&#xd7;Nwavelength selective switch (WSS) configuration in which switch elements are configured in a way that enables the input or output fibers to be arranged in a two-dimensional (2D) array. By employing 2D arrays of input/output channels, the channel count is increased from N to Nfor wavelength selective switches. In one embodiment, in which the components are arranged as a 2-f imaging system, a one-dimensional (1D) array of mirrors is configured such that each mirror has a dual scanning axis (i.e., each mirror can be scanned in X and Y directions). In another embodiment, in which the components are arranged as a 4-f imaging system, two 1D arrays of mirrors are configured with orthogonal scanning directions. In both embodiments, the number of ports is increased from N to N.

Wavelength-selective 1&#xd7;N2 switches with two-dimensional input/output fiber arrays

The periodic array of photodiodes are disposed in a passive optical waveguide electrically coupled in series with each other by microwave transmission line. The collective array of photodiodes coupled to the optical waveguide and microwave transmission line results in an increased bandwidth-efficiency product for the photodetector array as compared to any single photodetector within the array. High optical-to-electrical conversion efficiencies near unity are achieved at frequencies as high as several hundred GHz. High efficiencies are achieved by matching the group velocity of the optical waves within the optical waveguide with the group velocity of electrical signals being transmitted in the microwave transmission line by appropriate selection of the capacitance of each of the photodiodes. Power saturation is improved by decreasing the optical density within the active layer of the photodiodes. Optical coupling efficiencies from optical fibers into and from the optical waveguide are further improved by enlarging the optical mode size in the optical waveguide.

Highly efficient, ultrafast optical-to-electrical converter and method

Growing community of inventors

Moraga, CA, United States of America

Ming-Chiang Wu