Nippon Oil Company

Mineo Watase

Masao Nambu

Tatsuo Kinoshita

A process for preparing an artificial biological membrane in which an aqueous solution containing 6 wt % or more of polyvinyl alcohol having a degree of hydrolysis of not less than 95 mol % and an average polymerization degree of not less than 700 and containing a biological substance or a substance which does not hinder the gelation of the polyvinyl alcohol is subjected to a freezing step followed by a thawing step. Then, the mass thus obtained is further subjected to at least one additional cyclic processing step including the freezing and thawing steps. The product hydrogel is hard or not too soft and not swollen in water.

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Shizuoka, Japan

Mineo Watase