Ampliwise Inc.

Mindy Su

Xing Su

Kai Wu

An embodiment relates to system comprising: (i) a reaction mixture comprises: a) a target nucleic acid molecule; b) a forward primer complementary to a strand of the target nucleic acid molecule, the forward primer comprises a first molecular moiety at a 3' end, wherein the first molecular moiety is non-complementary to the strand of the target nucleic acid molecule; c) a reverse primer complementary to a complementary sequence of the strand of the target nucleic acid molecule, the reverse primer comprises a second molecular moiety at a 3&#x2032; end, wherein the second molecular moiety is non-complementary to the complementary sequence of the strand of the target nucleic acid molecule; d) a polymerase with 3&#x2032;-5&#x2032; exonuclease activity; and (ii a device suitable of detecting an amplification products.

Compositions and methods for nucleic acid amplification

The disclosure provides compositions and methods for amplifying and/or analyzing nucleic acids.

The disclosure provides compositions and methods for amplifying nucleic acids.

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Cupertino, CA, United States of America

Mindy Su