Toyama Chemical Co., Ltd.

Minako Yotsuji

Yasuo Kiba

Hiroshi Hirano

Shiro Hirai

Hirotoshi Arai

Hisanari Shibata

Kazuhiko Hashiba

Kikuko Tanada

Hiroshi Sakai

Hirokazu Narita

Hiroyuki Imaizumi

Tamotsu Takamatsu

Taro Kiyoto

Kenji Yonezawa

Kazuya Hayashi

Hironori Kotsubo

Junichi Mitsuyama

Hirohiko Yamamoto

Keiko Takakura

Akira Yotsuji

Katsuji Ojima

Tetsuya Kajita

Kyoko Taya

Kazuko Takaoka

Kenichi Takashima

Yoshikazu Kusayanag

Katsumi Shimizu

Minoru Yamada

Shoichi Hamamoto

Hiroko Matsukura

Yutaka Kodama

Toru Hiraiwa

Isao Kitayama

Nobuo Terashima

Tsutomu Kodama

Hajime Aoyama

Masaakira Senoura

Tomonobu Yamaguchi

Yoshikazu Kusayanagi

Masaharu Omori

PROCESSES FOR PRODUCING 7-ISOINDOLINE-QUINOLONECARBOXYLIC ACID DERIVATIVE AND ITS INTERMEDIATE, AS WELL AS SALT OF 7-ISOINDOLINE-QUINOLONECARBOXYLIC ACID DERIVATIVE, ITS HYDRATE AND COMPOSITION COMPRISING THE SAME AS ACTIVE INGREDIENT

Processes for producing 7-isoindolinequinolonecarboxylic derivatives and intermediates therefor, salts of 7-isoindolinequinolonecarboxylic acids, hydrates thereof, and composition containing the same as active ingredient

The present invention relates to a compound represented by the general formula (1) or its salt, a process for producing the same, and an antifungal agent comprising the same as an effective component: ##STR1## wherein R.sup.1 represents a substituted or unsubstituted aryl group or a substituted or unsubstituted heterocyclic group bonded through a carbon atom in the ring to the main chain; R.sup.2 presents a hydrogen atom, a fluorine atom or a substituted or unsubstituted alkyl group; and R.sup.3 represents a cyano group, a thioamido group or a group represented by the formula ##STR2## in which R.sup.4 is a hydroxyl group or a group of the formula ##STR3## (R.sup.7 and R.sup.8, which may be the same or different, are hydrogen atoms or substituted or unsubstituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, amino, alkoxy, hydroxyl or heterocyclic groups, and may form a substituted or unsubstituted heterocyclic group together with the nitrogen atom to which R.sup.7 and R.sup.8 attach), R.sup.5 is a substituted or unsubstituted alkoxy group or a group of the formula ##STR4## (R.sup.7 and R.sup.8 are as defined above), and R.sup.6 is a hydrogen atom or a substituted or unsubstituted alkyl group.

Triazole derivatives and salts thereof, and antifungal agent containing

Triazole derivatives and salts thereof and antifungal agent containing

This invention relates to amine derivatives and salts thereof. These compounds have an anti-ulcer activity which is effective to human beings and animals. This disclosure relates to such compound, a process for the preparation thereof and an anti-ulcer agent containing the same.

Amine derivatives, salts thereof, process for preparing the same and an

Novel amine derivatives, salts thereof and an anti-ulcer agent

This invention relates to amine derivatives and salts thereof. These compounds have an anti-ulcer activity which is effective to human beings and animals. This disclosure relates to such compounds, a process for the preparation thereof and an anti-ulcer agent containing the same.

Intermediates for urea and thiourea derivatives

5-Fluoro-(.beta.-uridine or 2'-deoxy-.beta.-uridine) derivatives having an acyl group at the 3-position of the molecule. These compounds are useful as carcinostatic agent. This disclosure relates to such compounds, a process for producing the same and a carcinostatic agent comprising such a compound.

5-Fluoro-(.beta.-uridine or 2'-deoxy-.beta.-uridine) derivatives, a

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Toyama, Japan

Minako Yotsuji