Hitachi Chemical Company, Ltd.

Osaka University

Tokyo Institute of Technology

Tokyo Medical and Dental University

Hitachi Chemical Research Center, Inc.

Mina Okochi

Tomoji Kawai

Masato Mitsuhashi

Masateru Taniguchi

Masayoshi Tanaka

Yoshinobu Baba

Makusu Tsutsui

Kazumichi Yokota

Taku Murakami

Takao Yasui

Yuji Miyahara

Noritada Kaji

Masafumi Yohda

Yukichi Horiguchi

Tsuruki Tamura

A device for biological material detection includes a substrate; a through-hole through which a biological material to be tested passes, the through-hole being formed in the substrate; a molecule that interacts with the biological material to be tested passing through, the molecule being formed in the through-hole; a first chamber member that forms, with at least the surface including the through-hole on one surface side of the substrate, a first chamber to be filled with electrolyte; and a second chamber member that forms, with at least the surface including the through-hole on the other surface side of the substrate, a second chamber to be filled with electrolyte. The biological material to be tested is identified by the waveform of the ion current (passage time, shape, etc.) when the biological material to be tested passes through the through-hole.

Device for biological material detection, detection apparatus for biological material detection, method for measuring ion current, and method for identifying biological material

A method and apparatus for concentrating dilute biomolecules in samples using electrophoresis are described. The method involves using the charged nature of the biomolecules to localize them to a microspot containing a dialysis membrane. The method and apparatus may also be used for identifying the presence of a biomolecule in a mixture or to quantitate the amount of a specific biomolecule in a mixture. The method and apparatus may also be used to produce a high throughput method for analysis and quantitation of a sample containing biomolecules.

Apparatus and method for electrophoretic microspot concentration

Growing community of inventors

Tokyo, Japan

Mina Okochi