Sk Chemicals Co., Ltd.

Tiumbio Co., Ltd.

Min-Young Han

Jae-Sun Kim

Jaeseung Ahn

Taekyung Yoo

Sung-Gi Kim

So-young Lee

Ju Young Lee

Yoo Jin Lee

Bong-Yong Lee

Hun-Taek Kim

Su-Min Lee

Je Ho Ryu

Seon-Mi Kim

Young-Ah Shin

Joon Ho Sa

Minhee Lee

Jeong A Lee

Euisun Park

Jung A Lee

Young Ah Shin

Dong-jin Han

Jeongmin Seo

So-Young Lee

The present invention relates to a polyester resin. The polyester resin is useful for bottles, sheets, multilayer sheets, stretched films and fiber applications due to excellent heat resistance and transparency, and in particular, the polyester resin has little deterioration of physical properties such as yellowing, etc., during processing. A process for making the polyester resin includes an esterification reaction between a dicarboxylic acid that includes terephthalic acid and a diol that includes isosorbide in the presence of a catalyst, followed by a polycondensation reaction on a product of the esterification reaction. In some embodiments, an initial mixing ratio of the dicarboxylic acid and the diol is between 1:1.02 and 1:1.04.

Polyester resin

The present invention relates to: a compound selected from the group consisting of a tricyclic compound having the structure of formula I, a pharmaceutically acceptable salt, an isomer, a solvate and a precursor thereof; and a use thereof. The compound effectively controls GPR40, and thus, can be effectively used for the prophylaxis or treatment of diseases associated with GPR40, for example, diabetes and many other diseases.

Tricyclic compound and use thereof

Disclosed are a gonadotropin releasing hormone receptor antagonist and a pharmaceutical composition including the same, which can be useful in preventing or treating a sex hormone-related disease such as endometriosis, amenorrhea, irregular menstruation, uterine myoma, uterine fibroids, polycystic ovarian disease, lupus erythematous, hypertrichosis, precocious puberty, short stature, acne, alopecia, gonadal steroid-dependent neoplasms, gonadotropin-producing pituitary adenoma, sleep apnea, irritable bowel syndrome, premenstrual syndrome, benign prostatic hyperplasia, contraception, and infertility, as well as Alzheimer disease.

Gonadotropin releasing hormone receptor antagonists, method for the preparation thereof and pharmaceutical composition comprising the same

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Seongnam-si, South Korea

Min-Young Han