Samsung Electronics Co., Ltd.

Samsung Bioepis Co., Ltd.

Min-Kyung Kim

A-yeon Cho

Jong-sang Ryu

Mi Young Cho

Brian Hosung Min

Kwang Ho Cheong

Jae-il Lee

Powei Lin

Seung Hyun Lee

Jung Wook Lee

Young Jun Koh

Jae Woong Hwang

Jung-Wook Lee

JungWook Lee

Chanmoo Lee

Jaeil Lee

Sangjoon Park

Brian Ho-sung Min

Seon-hui Shim

Jung-wook Lee

SuJeong Hwang

Su Jeong Hwang

Seon-Hui Shim

A fusion polynucleotide including a murine CMV promoter and an intron, a recombinant vector including the fusion polynucleotide and a gene encoding a polypeptide of interest, a recombinant cell including the recombinant vector, and a method of producing a polypeptide of interest using the recombinant vector and/or the recombinant cell.

Fusion polynucleotide containing murine CMV promoter and method of preparing a polypeptide of interest using the same

A bispecific antigen binding protein complex comprising a first polypeptide comprising a first antigen binding site at an N terminus; a second polypeptide comprising a second antigen binding site at an N terminus; and a linker connecting the first polypeptide and the second polypeptide; wherein the linker comprises a tag at one terminus thereof, and wherein the tag is connected to a C-terminus of the first polypeptide or to an N-terminus of the second polypeptide, and comprises a cleavable amino acid sequence; as well as related compositions and methods.

Bispecific antigen binding protein complex and preparation methods of bispecific antibodies

A protein complex comprising (i) a first fusion protein comprising (a) a first polypeptide that comprises a first antigen-binding site and (b) a first binding protein linked to a terminus of the first polypeptide; and (ii) a second fusion protein comprising (a) a second polypeptide that comprises a second antigen-binding site and (b) a second binding protein linked to a terminus of the second polypeptide, wherein the protein complex comprises an amino acid sequence that enables cleavage between the first polypeptide and the first binding protein, and/or between the second polypeptide and the second binding protein, as well as a method for preparing a bi-specific antibody and related methods and compositions.

Protein complexes and methods of manufacturing bispecific antibodies using the protein complexes

Provided is an anti-Her3 antibody or antigen-binding fragment thereof, an anti-c-Met/anti-Her3 bispecific antibody including the same, and a method of preventing and/or treating a cancer using the same.

Anti-Her3 scFV fragment and bispecific anti-c-Met/anti-Her3 antibodies comprising the same

A bispecific chimeric protein including a designed ankyrin repeat protein (DARPin), and an IgG antibody, an scFv-Fc antibody fragment, or a combination thereof, linked to the DARPin; a method for treating or preventing cancer using the same; and related methods and compositions.

Bispecific chimeric proteins comprising DARPins

Provided is a method of screening a target-specific antibody for an antigen that undergoes structural change in a particular physiological condition.

Method of screening antibodies with high antigen selectivity

A polypeptide inhibiting binding between vascular endothelial growth factor receptor-2 and a vascular endothelial growth factor, a fusion protein including the same, and a method of preparing the fusion protein are disclosed.

Polypeptides specifically binding to vascular endothelial growth factor receptor-2 and methods therefor

An antibody specifically binding to angiopoietin-2, and antigen-binding fragments thereof, and a use thereof are disclosed.

Antibody specifically binding to angiopoietin-2 and use thereof

A polypeptide inhibiting binding between a vascular endothelial growth factor and a vascular endothelial growth factor receptor, a fusion protein including the same, and a method of preparing the fusion protein are disclosed.

Growing community of inventors

Seoul, South Korea

Min-Kyung Kim