Gwangju Institute of Science and Technology

Nspc Technologies, LLC

Ingibio, Ltd.

Korea University Research and Business Foundation

Korea Research Institute of Bioscience and Biotechnology

Min-Gon Kim

Hyou-Arm Joung

Hyo-Young Mun

Ju Young Byun

Eun-Jung Jo

Jin-Ho Park

Jun-Hyoung Ahn

Jungbae Kim

Yun Ju Sung

Ho-Jun Suk

Yongho Wee

Young-Kyoung Oh

Dong-Gu Hong

Ju-Young Byun

Taihua Li

The invention encompasses methods and test strips for detecting the presence of cerebrospinal fluid (CSF) in a biological sample with a lateral flow device which uses lectin conjugates, anti-antigen conjugates, an immobilized serum line, and an immobilized anti-antigen line.

Assay for rapid detection of cerebrospinal fluid leaks

Disclosed is a platform detecting glycated hemoglobin as an indicator for diabetes in the blood based on upconverting nanoparticles excited by near-infrared light and luminescence resonance energy transfer.

Composite compound comprising upconverting nanoparticle and specific receptor

Disclosed herein is an aptamer sensor including a substrate having metal nanoparticles formed thereon, an aptamer attached to surfaces of the metal nanoparticles to form a structure by selectively reacting with a target material to be detected, and an intercalating agent inserted between the aptamer and the target material in reaction of the aptamer with the target material to increase shift of an absorption spectrum due to local surface plasmon resonance sensor through aggregation toward the metal nanoparticles.

LSPR-based high sensitivity aptamer sensor using intercalation agent

The present disclosure relates to a complex for detecting a target material comprising upconverting nanoparticles; and at least one target material specific aptamer-quencher, connected through a linker with the upconverting nanoparticles, a method of preparing the same, a kit for detecting a target material comprising the same, and a method of detecting a target material using the same. According to the present disclosure, different target materials in samples can be quantified or detected accurately based on luminescence resonance energy transfer (LRET) of the upconverting nanoparticles (UCNPs) excited by a near infrared (NIR) light source.

Complex for detecting target material and method of detecting target material using the same

Provided is a method for manufacturing a multiple-diagnosis membrane sensor provided with multiple channels by using screen printing, and more specifically, to a method for manufacturing a membrane sensor capable of performing multiple-diagnosis by screen-printing hydrophobic ink on a membrane to form multiple channels. The membrane sensor according to the present invention may enable mass-production of sensors and secure reliability of detection by forming the plurality of channels on the membrane by a simple method.

Method for manufacturing multiple-diagnosis membrane sensor by using screen printing

The present disclosure provides an optical biosensor based on a complex including a porous support on a chip and enzyme(s) immobilized inside the pores of the porous support, and a method for preparing the same. Since the colored product does not flow out of the pores but is concentrated therein, the optical biosensor of the present disclosure has remarkably improved sensitivity. In addition, it is possible to carry out quantitative determination and qualitative analysis since color intensity increases with time.

Optical biosensor

Disclosed herein are a method for manufacturing a multi-functional bio-material conjugate used as a biosensor for detecting microorganisms, and the like, and a multi-functional bio-material conjugate manufactured by means of the same. The method for manufacturing a multi-functional bio-material conjugate includes: (a) coating a first nanoparticle having magnetic or fluorescent characteristics with protein; (b) manufacturing a conjugate by adsorbing a second nanoparticle having metallic characteristics onto the first nanoparticle coated with protein; and (c) manufacturing the multi-functional bio-material conjugate by adsorbing a bio-material onto the conjugate. The method for manufacturing a multi-functional bio-material conjugate according to the present invention may prevent precipitation of the nanoparticles, easily immobilize the bio-material, and manufacture a bio-material conjugate having multiple functions, by using two kinds of the particles. In addition, the multi-functional bio-material conjugate manufactured by the present method may be used to detect microorganisms at up to a concentration of 10cfu.

Method for manufacturing multi-functional bio-material conjugate using two kinds of particle, and multi-functional bio-material conjugate manufactured by means of same

Disclosed herein are a membrane sensor capable of changing a reaction condition by a single sample injection and a method for measuring a reaction using the same, and more specifically, a membrane sensor designed so that a bio reaction having two or more reaction conditions is sequentially generated by a single sample injection, by forming an asymmetric membrane between a reactant storing part and a reaction membrane.

Membrane sensor capable of sequentially changing reaction condition by single sample injection

Provided are a method of analyzing a target substance to be measured, the method including: dividing a surface of a measuring unit of a CMOS image sensor into a plurality of pixels, directly fixing a bioreceptor onto the surface of the measuring unit of the CMOS image sensor, and measuring chemiluminescent signals depending on concentrations of the target substance to be measured, and a CMOS image sensor applied to the same.

High sensitivity biosensor using pixel analysis of CMOS image sensor

Provided are a titanium dioxide-coated upconverting nanoparticle (UCNP) and a photocatalyst complex containing a gold nanorod (GNR) combined with the titanium dioxide-coated UCNP.

Growing community of inventors

Gwangju, South Korea

Min-Gon Kim