Cardiac Pacemakers, Inc.

Neuspera Medical Inc.

The UAB Research Foundation (The University of Alabama at Birmingham)

Milton M Morris

Alexander Jueshyan Yeh

Yinghong Yu

Jiang Ding

Victor T Chen

Gary Thomas Seim

Bruce H KenKnight

Timothy A Fayram

Alan F Marcovecchio

David S Wood

Mudit Jain

Elia Junco

Steven D Girouard

Douglas J Lang

Brad Holinski

Randolph Kerry Armstrong

Gary Shaw

Raymond E Ideker

Lynn H Elliott

Gregory P Walcott

Jeffrey A Hall

Michael E Benser

Shivkumar Sabesan

Thomas Burpee Ellsworth, Iii

Stephen James Schellenberg

Kevin Collins

Hui Zhang

Systems, devices, and methods discussed herein can be for validating a position of a wirelessly powered electrostimulation device while the device is implanted in body tissue. A method can include situating the electrostimulation device in tissue and before an affixation mechanism of the electrostimulation device is deployed to maintain an implanted position of the electrostimulation device, and while electrodes of the device are in contact with the tissue, performing electrical testing of the electrostimulation device to determine whether the electrostimulation from the electrostimulation device evokes a specified response from the body that contains the tissue.

Wireless implantable device position validation in situ

Described herein are devices, systems, and methods for wireless power transfer utilizing a midfield source and implant. In one variation, a midfield source may be realized by a patterned metal plate composed of one of more subwavelength structures. These midfield sources may manipulate evanescent fields outside a material (e.g., tissue) to excite and control propagating fields inside the material (e.g., tissue) and thereby generate spatially confined and adaptive energy transport in the material (e.g., tissue). The energy may be received by an implanted device, which may be configured for one or more functions such as stimulation, sensing, or drug delivery.

External power devices and systems

Generally discussed herein are systems, devices, and methods for providing a therapy (e.g., stimulation) and/or data signal using an implantable device. Systems, devices and methods for interacting with (e.g., communicating with, receiving power from) an external device are also provided.

Devices, systems, and methods for stimulation therapy

Generally discussed herein are systems, devices, and methods for providing a therapy or data signal using an implantable device. A method of providing intermittent stimulation by a stimulation system can include providing, by an external device of the stimulation system, radio frequency first signals to an implantable device of the stimulation system, the implantable device including an electrode and the first signals causing the implantable device to provide electrical stimulation through the electrode for a first time duration, determining, at the external device, that the implantable device is out of range of a transmission from the external device, determining, at the external device, that the implantable device is within range of the transmission from the external device, and providing, by an external device of the stimulation system, radio frequency second signals to the implantable device of the stimulation system, the second signals causing the implantable device to provide electrical stimulation through the electrode for a third time duration.

Midfield coupler

Wireless energy transfer system for an implantable medical device using a midfield coupler

A pacing system computes optimal cardiac resynchronization pacing parameters using intrinsic conduction intervals. In various embodiments, values for atrio-ventricular delay intervals are each computed as a function of an intrinsic atrio-ventricular interval and a parameter reflective of an interventricular conduction delay. Examples of the parameter reflective of the interventricular conduction delay include QRS width and interval between right and left ventricular senses.

Method and system for delivering cardiac resynchronization therapy with variable atrio-ventricular delay

A system and method for identifying patients with asynchronous ventricular contractions due to abnormal electro-mechanical coupling and computing optimal pacing parameters for restoring synchronous contractions is disclosed. Such patients may have normal intra-ventricular and inter-ventricular conduction and cannot be identified from intrinsic conduction data alone such as QRS width. Techniques for computing optimal resynchronization pacing in order to compensate for abnormal electro-mechanical coupling are also described.

Method and system for treatment of mechanical cardiac asynchrony

An implantable heart-monitoring device comprising one or more leads for sensing electrical signals of a patient's heart a therapy circuit for delivering pharmaceuticals to the patient; and a monitoring circuit coupled to the one or more leads and to the therapy circuit, the monitoring circuit for monitoring heart activity of the patient through one or more of the leads, the monitoring circuit operable to: determine a minimum interval from a set of two or more intervals based on sensed heart activity, determine a range parameter based on a difference between a first subset and second subset of the intervals, determine a dispersion parameter quantifying dispersion of a subset of the intervals, and to determine an assessment value for the set of intervals, based on the minimum interval, the range parameter, the dispersion index.

Therapy-selection methods for implantable heart monitors

A system and method for providing pacing pulses after a cardioversion/defibrillation shock, where the pacing pulses have a pacing rate at an initial value. The pacing rate is decreased from the initial value until at least one intrinsic cardiac contraction is detected. In one embodiment, the pacing rate is decreased by a set amount after pacing a set number of cardiac cycles. Providing the set number of pacing pulses and decreasing the pacing rate by the set amount is then repeated until at least one intrinsic cardiac contraction is detected. An intrinsic cardiac rate is then determined from the at least one intrinsic cardiac contraction. The pacing rate is then increased and maintained to be above (i.e., greater than) the intrinsic cardiac rate.

System and method for preventing recurrence of atrial tachyarrhythmia

A system and method which employs atrial discrimination algorithms to distinguish between different atrial arrhythmias occurring in a patient for selecting an optimal pacing therapy corresponding to the type of arrhythmia identified. In response to the detection of an atrial rate above the atrial tracking rate, discrimination criteria are applied to a detected atrial activity signal to distinguish between different types of supraventricular tachycardia, such as fast atrial flutter and other atrial flutter at a relatively slower rate, which may be occurring in the patient. The pacer is controlled to provide pacing therapy to a heart in a manner corresponding to the type of supraventricular tachycardia identified. The output of an atrial discrimination algorithm may be tracked and the trend thereof used to improve therapy timing. Various embodiments are disclosed herein.

Method and apparatus for using atrial discrimination algorithms to determine optimal pacing therapy and therapy timing

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Minneapolis, MN, United States of America

Milton M Morris