Memorial Sloan Kettering Cancer Center

Montana State University

Physical Sciences, Inc.

Abeytunge, Sanjee

Milind Rajadhyaksha

Ricardo Toledo-Crow

Snehal G Patel

Sanjee Abeytunge

Nicusor V Iftimia

R Daniel Ferguson

David L Dickensheets

Mircea Mujat

Yongbiao Li

Bjorg Larson

Ricardo Toledeo-Crow

Ankit H Patel

David Dickensheets

Yonkgiao Li

A device for viewing a target, the device including a housing, an objective lens positioned within the housing, where the objective lens has a first lens group including at least a first lens and a second lens group including at least a second lens, the first lens positioned closer to the target than the second lens, and a camera positioned within the objective lens between the first lens and the second lens, where the camera is configured to provide images of the target located near a focal point of the objective lens, and wherein the arrangement of the first lens, the second lens, and the camera provides for simultaneous capture of a first image of a surface of the target and a second image of a sub-surface cellular structure of the target.

Microscope lens with integrated wide-field camera and beam scanning device

Handheld devices and methods that integrate wide-field dermoscopy with reflectance confocal microscopy for non-invasive simultaneous capture of wide-field color images of the skin surface and images of the sub-surface cellular structure.

Provided and described herein are exemplary embodiments of apparatus, system, computer-accessible medium, procedure and method according to the present disclosure which can be used for providing laser steering and focusing for e.g., incision, excision and/or ablation of tissue in minimally-invasive surgery. For example, an exemplary apparatus is provided that can include at least one optical element which can be configured to refract and/or diffract light provided in a structure which can be configured to be inserted into a body, where at least one of the optical element(s) is structured to receive the light at a first angle and generate a refracted and/or diffracted light at a second angle which can be different from the first angle relative to an optical axis. According to a particular exemplary embodiment of the present disclosure an exemplary actuating arrangement can be provided, which can be configured to control the optical element(s), can be provided and seated at least partially within the at least one structure.

Apparatus, system and method for providing laser steering and focusing for incision, excision and ablation of tissue in minimally-invasive surgery

Provided and described herein are exemplary embodiments of apparatus, system, computer-accessible medium, procedure and method according to the present disclosure which can be used for providing laser steering and focusing for, e.g., incision, excision and/or ablation of tissue in minimally-invasive surgery. For example, an exemplary apparatus is provided that can include at least one optical element which can be configured to refract and/or diffract light provided in a structure which can be configured to be inserted into a body, where at least one of the optical element(s) is structured to receive the light at a first angle and generate a refracted and/or diffracted light at a second angle which can be different from the first angle relative to an optical axis. According to a particular exemplary embodiment of the present disclosure, it is possible to control a light propagating arrangement to (i) provide the at least one light toward the optical element(s) at the first angle, and (ii) change a position thereof within the structure(s) to change the first angle.

Exemplary systems, methods and non-transitory computer-accessible mediums are provided for generating a mosaic image of a large area of tissue with microscopic resolution by acquiring a plurality of rectangular-shaped long strips of images of the tissue and stitching the strips together along their lengths.

System, method and computer readable medium for imaging large areas with microscopic resolution

Exemplary embodiments of apparatus and method for facilitating an analysis of a sample(s) can be provided. For example, using a first arrangement(s), it can be possible to receive the sample(s) thereon. Further, for example, using a second arrangement(s), it can be possible to cause a force to be applied on a portion(s) of the sample(s) such that a surface(s) of the sample(s) can be flattened against a section(s) of the first arrangement(s).

Devices applicable to tissue(s) which facilitates confocal microscopy, optical microscopy, spectroscopy and/or imaging

A dual-modality apparatus for imaging of biological tissue includes a reflectance confocal microscopy (RCM) imaging apparatus and an optical coherence tomography (OCT) imaging apparatus. A first optical component reflects a first beam of light provided by a RCM imaging apparatus towards a sample and passes a second beam of light provided by an OCT imaging apparatus towards the sample, such that the first and second beam of lights share at least a portion of an imaging path.

Combined reflectance confocal microscopy-optical coherence tomography system for imaging of biological tissue

Exemplary embodiments of apparatus, system, computer-accessible medium, procedure and method are provided which can be used for providing laser steering and focusing for, e.g., incision, excision and/or ablation of tissue in minimally-invasive surgery. For example, the exemplary apparatus can include at least one optical element which can be configured to refract and/or diffract light provided in a structure which can be configured to be inserted into a body, where at least one of the optical element(s) is structured to receive the light at a first angle and generate a refracted and/or diffracted light at a second angle which can be different from the first angle relative to an optical axis. For example, an actuating arrangement can be provided, which can be configured to control the optical element(s), can be provided and situated at least partially within the at least one structure.

Growing community of inventors

New York, NY, United States of America

Milind Rajadhyaksha