Galena as

Ivax Pharmaceuticals S.r.o.

Agra Group, A.s.

Milan Stuchlik

Kvetoslava Benesova

Ales Husek

Josef Stuchlik

Vladimir Matha

Tomas Andrysek

Alexandr Jegorov

Jiri Kopenec

Ladislav Cvak

Alexander Jegorov

Tom&aacute;s Andr&yacute;sek

Zdenek Pavelek

Lubos Markovic

The invention relates to a composition containing flavanolignans, e.g., isolated from, and basic amino acids and, optionally, other auxiliary substances, in the form of mixture, and to the method of preparation of these compositions by mixing the components and their homogenization. The invention is applicable particularly in the pharmaceutical industry, cosmetics, food industry, breweries, distilleries, and in the industry of beverage production.

Composition of flavanolignan and amino acid with improved water solubility

The inventors have devised novel approaches for the preparation of flavanolignan compositions of enhanced solubility and substantially free of toxic contaminants. Such novel approaches are based on spray drying or lyophilizing to dry a diluted preparation of flavanolignan. These approaches avoid the use of toxic excipients and or carriers commonly used to precipitate flavanolignan concentrates and thus address the drawbacks of existing methods and compositions.

Increased solubility flavanolignan preparations

Immunomodulatory pharmaceutical composition adopted to form lyotrophic liquid crystals in contact with an aqueous phase

Provided are therapeutic compositions which provide high bioavailability of the active ingredients from the group of cyclosporin, at the same time permitting concentrations in dosage forms higher than 10%.

Cyclosporin formulation

Pharmaceutical containing N-methylated cyclic undecapeptides

Growing community of inventors

Opava, Czechia

Milan Stuchlik