Mc10, Inc.

Epicore Biosystems, Inc.

Medidata Solutions, Inc.

Milan S Raj

Roozbeh Ghaffari

Bryan McGrane

Jeffrey B Model

Alexander J Aranyosi

Valerie Susan Hanson

Bryan Keen

Hoi-Cheong Steve Sun

Stephen P Lee

Melissa Ceruolo

Ryan S McGinnis

Shyamal Patel

Xianyan Wang

Gilbert Lee Huppert

Brian Murphy

Aadithya Prakash

Briana Morey

Elise Jortberg

Ikaro Silva

Yung-Yu Hsu

Conor S Rafferty

Donald Fuchs

Isaiah Kacyvenski

Ping-Hung Wei

Monica Lin

PingHung Wei

Brian Reilly

Emily Plumb

A sweat sensing device includes a flexible body having a first, outwardly facing surface and a second, skin facing surface and a sweat channel formed in the body, the sweat channel having a first end defining a fluid inlet and a second end. A biochemical assay well formed in the sweat channel and an assay material is disposed in the biochemical assay well, the assay material positioned to react with sweat traveling through the sweat channel and to provide one of a visual indicator and an indicator detectable by a camera and connected processor of the flow of the sweat in the sweat channel.

Wearable fluidic system for measuring sweat composition

A sweat collection device includes a flexible body having a first, outwardly facing surface and a second, skin-facing surface, and a sweat collection channel formed in the body, the sweat collection channel having a first end defining a sweat inlet port, and a second end defining a sweat outlet port. The sweat inlet port and the sweat outlet port are configured to be closed and sealed such that the sweat collection device and the collected sweat therein may be stored and shipped.

Wearable fluidic device and system for sweat collection and extraction

An electronic device worn on a user includes one or more accelerometers. The one or more accelerometers generate acceleration information based on acceleration experienced by the electronic device. The electronic device further includes a processor and one or more associated memories, and the one or more associate memories include computer program code executable by the processor. The processor, configured by the computer program code, causes the electronic device to process the acceleration information to extract features from the acceleration information. The processor, configured by the computer program code, further causes the electronic device to process the features to determine the location of the electronic device on the user.

Automated detection and configuration of wearable devices based on on-body status, location, and/or orientation

Wearable heat flux devices are disclosed that can detect heat flux based on evaporative cooling for determining a core body temperature of a user, and that can heat or cool a surface of a user for reaching a steady-state heat flux to determine the core body temperature of the user. Exemplary heat flux devices can include a heat flux sensor and a wicking layer. The heat flux sensor can be configured to detect heat flux at a location on a user. The wicking layer can be configured to absorb moisture at the location and to transport the moisture above the heat flux sensor. The heat flux subsequently detected by the heat flux sensor includes the evaporative cooling from the evaporation of the moisture.

Wearable heat flux devices and methods of use

An on-body sensor system includes a hub configured to be attached to a surface of a user. The hub being further configured to transmit electrical power and data signals into the surface and to receive response data signals from the surface. The system further including at least one sensor node configured to be attached to the surface or just below the skin. The system further including at least one sensor node being further configured to receive the electrical power and data signals from the hub through the surface and to transmit the response data signals into the surface. The electrical power from the hub powers the at least one sensor node and causes the at least one sensor node to generate sensor information that is transmitted back to the hub within the response data signals.

System, device, and method for coupled hub and sensor node on-body acquisition of sensor information

A device includes a flexible printed circuit board and one or more conductive stiffeners. The conductive stiffeners include a conductive surface that can be electrically connected to contact pads on the flexible printed circuit board. The wearable device can further include an adhesive layer or an encapsulation layer. The adhesive layer and the encapsulation layer can include conductive portions surrounded by non-conductive portions. The conductive portions can be aligned with the conductive stiffeners and together transmit electrical energy to the contact pads of the flexible printed circuit board.

Conductive stiffener, method of making a conductive stiffener, and conductive adhesive and encapsulation layers

An on-body sensor system includes a hub configured to be attached to a surface of a user. The hub being further configured to transmit electrical power and/or data signals into the surface and to receive response data signals from the surface. The system further including at least one sensor node configured to be attached to the surface. The sensor node being further configured to receive the electrical power and data signals from the hub through the surface and to transmit the response data signals into the surface. The electrical power from the hub can power the sensor node and cause or enable the at least one sensor node to generate sensor information that is transmitted back to the hub within the response data signals.

System, devices, and method for on-body data and power transmission

A system for controlling a therapeutic device and/or environmental parameters can include one or more body worn sensor devices that detect and report one or more physical, physiological, or biological parameters of a person in an environment. The sensor devices can communicate sensor data indicative of the one or more physical, physiological, or biological parameters of a person to an external hub that processes the data and communicates with the therapeutic device to provide a therapy (e.g., neuromodulation, neurostimulation, or drug delivery) as a function of the sensor data. In some embodiments, the therapeutic device can be implanted in the person. In some embodiments, the therapeutic device can be in contact with the skin of the person. The sensor devices can also communicate to the hub that communicates with one or more devices to change the environment as a function of the sensor data.

Method and system for neuromodulation and stimulation

Conformal sensor systems and devices are used for sensing and analysis of data indicative of body motion, e.g., for such applications as training and/or clinical purposes. Flexible electronics technology can be implemented as conformal sensors for sensing or measuring motion (including body motion and/or muscle activity), heart rate, electrical activity, and/or body temperature for such applications as medical diagnosis, medical treatment, physical activity, physical therapy and/or clinical purposes. The conformal sensors can be used for detecting and quantifying impact, and can be used for central nervous system disease monitoring.

Conformal sensor systems for sensing and analysis

A wireless charging system for a wearable sensor device can include a wireless charging device and a user device. The wireless charging device can include a transmitter for sending a power signal to charge the wearable sensor device, a first receiver to receive a data signal and a second to receive a low energy signal. The wearable sensor device can include at least one memory for storing sensor data, a first receiver for receiving the power signal from the wireless charging device, a first transmitter to transmit a data signal and a second receive to receive a low energy signal. The user device can include a low energy transmitter for communicating with the wireless charging device and sensor device to control the charging function and the data communication function of the wireless charging device to selectively charge and transfer data with wearable sensor device.

Wireless charger and high speed data off-loader

A system for providing a more personalized virtual environment for a user, the system including one or more sensing devices that detect one or more physical, physiological, or biological parameters of the user and transmit the same to a game console or virtual reality controller that produces the virtual environment. The game console or virtual reality controller can analyze the sensor data and adjust one or more aspects of the virtual environment as a function of the sensor data. For example, the difficulty level or scariness level of a game can be decreased if the heart rate of the user exceeds a predetermined threshold.

Method and system for interacting with a virtual environment

Systems, methods and apparatuses for monitoring cardiac activity of an individual using a conformal cardiac sensor device are presented herein. A conformal cardiac sensor device for analyzing cardiac activity includes a flexible substrate for coupling to the user, and a heart sensor component embedded on/in the substrate. The heart sensor component contacts a portion of the user's skin and measures electrical variable(s) indicative of cardiac activity. A biometric sensor component is embedded on/in the flexible substrate and measures physiological variable(s) indicative of cardiac activity of the user. A microprocessor, which is embedded on/in the flexible substrate, is communicatively coupled to the heart sensor component and biometric sensor component and operable to execute microprocessor executable instructions for controlling the measurements of electrical data and physiological data. A wireless communication component is embedded on/in the flexible substrate and is operable to transmit data indicative of the measurements obtained by the sensor components.

Conformal sensor systems for sensing and analysis of cardiac activity

Systems, methods and apparatuses for monitoring cardiac activity of an individual using a conformal cardiac sensor device are presented herein. A conformal cardiac sensor device for analyzing cardiac activity includes a flexible substrate for coupling to the user, and a heart sensor component embedded on/in the substrate. The heart sensor component contacts a portion of the users skin and measures electrical variable(s) indicative of cardiac activity. A biometric sensor component is embedded on/in the flexible substrate and measures physiological variable(s) indicative of cardiac activity of the user. A microprocessor, which is embedded on/in the flexible substrate, is communicatively coupled to the heart sensor component and biometric sensor component and operable to execute microprocessor executable instructions for controlling the measurements of electrical data and physiological data. A wireless communication component is embedded on/in the flexible substrate and is operable to transmit data indicative of the measurements obtained by the sensor components.

Growing community of inventors

Natick, MA, United States of America

Milan S Raj