Spofa, Spojene Podniky Pro Zdravotnickou Vyrobu

Vyzkumny Ustav Pro Farmacii a Biochemii

Spojene Podniky Pro Zdravotnickou Vyrobu

Milan Pesak

Jiri Krepelka

Evzen Kasafirek

Ivan Krejci

Arnost Pospisil

Karel Rezabek

Antonin Cerny

Antonin Dlabac

Bohumil Sevcik

Josef Kral

Martin Valchar

Josef Picha

Antonin Sturc

Jiri Vanzura

Jirina Cizkova

Maria Fruhaufova

Vaclav Plaisner

Karel Dobrovsky

Josef Stuchlik

Zdenek Hlinak

Antonin Borovicka

Jana Strakova

Petr Bilek

Jirj Kohout

Antonin Struc

Dagmar Picmausova

Libuse Korbova

The present application is directed to a method of treating central nervous system disorders originating as a consequence of head injury or brain ischemia. The method comprises administering an effective amount of cyclo-(L-alanyl-1-amino-1-cyclopentane carbonyl) to treat a central nervous system disorder in a mammalian organism in need of such treatment. The administration may be conducted either orally or parenterally.

Neuroprotective composition for preventing or treating of central

A cell-protective composition for preventing or treating of a peptic ulcer due to topical endogenous lesion of gastric or duodenal mucous membrane comprises as a physiologically active component the cyclo-(1-alanyl-amino-1-cyclopentanecarbonyl)cyclodipeptide. The subject composition is designated for administration by oral or parenteral route. It is substantially non-toxic and well tolerated, and acts beneficially, even at low dosage level.

Cell-protective composition for preventing or treating of peptic ulcer

This invention relates to a method for the treatment of endometritis (chronic and/or acute puerperal inflammations) in mammalian females comprising the administration of 1-(8-alpha-ergolinyl)-3,3-diethylurea derivatives of Formula I ##STR1## in which R.sup.1 represents an alkyl group containing 1 to 3 carbon atoms, R.sup.2 represents a hydrogen atom or an alkyl group containing 1 to 3 carbon atoms, and X represents a hydrogen atom or a double bond between the carbon atoms at positions 9 and 10. The compound according to Formula I, or a pharmaceutically acceptable acid addition salt thereof, is the physiologically active component of the therapeutic composition and method. The compound may be combined with a pharmaceutically acceptable diluent, vehicle, excipient, auxiliary, or carrier. The invention is particularly advantageous in veterinary medicine, when applied to the treatment of farm animals, such a cows.

Method for treatment of endometritis in mammalian females

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Praha, Czechoslovakia

Milan Pesak