Richter Gedeon Vegyeszeti Gyar Rt

Stichting Rega Vzw

Borsodi Vegyi Kombinat

Miklos Nagy

Miklos Low

Sandor Gorog

Masanori Baba

Erik D De Clercq

Sandorne Gyorgyi

Laszlo Szporny

Egon Karpati

Lajos Kisfaludy

Istvan Horvath

Katalin Csomor

Gaborne Kovacs

Laszlone Jaksity

Miklos Zrinyi

Ervin Wolfram

Judit Gyorgyi Nee Edelenyi

Raymund Machovich

Janos Toth

Laszlo Molnar

Bela Mariasi

Imre Gulya

Sulphated vinyl polymers such as sulphated polyvinylalcohol, sulphated copolymers of (meth)acrylic acid and vinylalcohol, and pharmaceutically acceptable salts thereof, have an antiviral effect against human immunodeficiency virus and may therefore be used as a therapeutic agent for treating retrovirus infections like AIDS and AIDS-related diseases. Their antiviral activity is apparently based on inhibition of virus adsorption; their inhibitory effect on giant cell formation is stronger than that of dextran sulphate.

Sulphated vinyl polymer in composition for treating retroviral infections

Sulphated vinyl polymers in compositions for treating retroviral

The invention relates to new, pharmaceutically active copolymers with heparin-like activity, pharmaceutically acceptable salts thereof and a process for their preparation. The new copolymers comprise the units of the formula I ##STR1## wherein X stands for hydrogen or methyl and Y is hydrogen, units of the formula III ##STR2## optionally units of the formula II ##STR3## wherein Z' is hydrogen, and chain terminating units, formed from the units of the formulae I, III and optionally II under the conditions of copolymerization, in a statistical arrangement, and the pharmaceutically acceptable salts thereof, which contain, in addition to the above chain-members, units of the formulae IV and/or V ##STR4## wherein A is a cation/ satisfactorily replace the organogenic heparin, or give a synergistic combination with that,

Pharmaceutically active copolymers, process for their preparation and

This invention relates to novel partially saponified polyvinyl acetates with a degree of hydrolysis of 30 to 65 mole % which might be considered as vinyl alcohol-vinyl acetate block copolymers. The invention relates further to the application of said novel block copolymers as a pore-forming additive used together with at least one known protective colloid in the homo- and copolymerization of vinyl compounds, primarily of vinyl chloride in a pure aqueous medium.

Partially saponified polyvinyl acetates and their application in the

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Budapest, Hungary

Miklos Nagy