Synthetic Genomics, Inc.

Mikkel A Algire

J Craig Venter

Hamilton O Smith

Daniel Glenn Gibson

Clyde A Hutchison

John Irvin Glass

Ray-Yuan Chuang

Vladimir N Noskov

Carole Lartigue

Gwynedd A Benders

Charles E Merryman

Sanjay Vashee

John I Glass

Compositions and methods are disclosed herein for cloning a donor genome in a heterologous host cell. In one embodiment, the donor genome can be further modified within a host cell. Modified or unmodified genomes can be further isolated from the host cell and transferred to a recipient cell. Methods disclosed herein can be used to alter donor genomes from intractable donor cells in more tractable host cells.

Methods for cloning and manipulating genomes

Compositions and methods are disclosed herein for cloning a synthetic or a semi-synthetic donor genome in a heterologous host cell. In one embodiment, the donor genome can be further modified within a host cell. Modified or unmodified genomes can be further isolated from the host cell and transferred to a recipient cell. Methods disclosed herein can be used to alter donor genomes from intractable donor cells in more tractable host cells.

Growing community of inventors

Jessup, MD, United States of America

Mikkel A Algire