Nippon Suisan Kaisha, Ltd.

Taisho Pharmaceutical Co., Ltd.

Mochida Pharmaceutical Co., Ltd.

Mikio Satake

Yoshiyuki Chiba

Masakazu Sato

Jun Goto

Takeshi Imanishi

Yutaka Kawashima

Chuzo Iwata

Tsuyoshi Koriyama

Seiichi Tokura

Yasuhiro Kohama

Tsutomu Mimura

Yasukazu Nagase

A sulfonamide derivative represented by the Formula: ##STR1## wherein A, B, X, Y, R, m and n are as defined in the specification, and a salt thereof have thromboxane A.sub.2 antagonism, therefore they are useful, for example, as blood platelet aggregation inhibiting agents.

Sulfonamide derivatives

A novel peptide possessing excellent antihypertensive activity is disclosed. The peptide has the formula:

Octopeptide exhibiting antimypertensive activity

A triazole derivative represented by the formula ##STR1## wherein R.sup.1 is a hydrogen atom, a lower alkyl group having 1 to 4 carbon atoms, an acetyl group, a naphthylmethyl group, an anthrylmethyl group or a group of the formula ##STR2## wherein X, Y and Z are the same or different and each a hydrogen atom, a halogen atom, a lower alkyl group having 1 to 4 carbon atoms, a lower alkoxy group having 1 to 4 carbon atoms, a hydroxyl group, a nitro group, a trifluoromethyl group, a cyano group or a benzyloxy group, and R.sup.2 is a hydrogen atom or an acetyl group, and R.sup.3 is a hydrogen atom, an acetyl group or a group of the formula ##STR3## wherein R.sup.1 and R.sup.2 are as defined above, are useful as the inhibitors of lipid peroxidation.

3,5-diamino-1,2,4-triazole derivatives

A novel squid chitin formed material is disclosed. Squid chitin is prepared by pulverizing squid crust and treating the pulverized chitin with caustic soda and then with hydrochloric acid to remove proteins and ashes. Squid chitin formed material such as sheet or fiber is then prepared by a freeze-defrost treatment. The squid chitin sheet and fiber have better physical properties than conventional crab chitin formed materials in terms of strength and folding endurance.

Squid chitin formed material

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Hachioji, Japan

Mikio Satake