Jsr Corporation

Mikio Hikata

Satoshi Katayose

Kejun Fan

Yasuhiro Furuichi

Kiyoshi Kasai

Ichiro Ozaki

Ichirou Ozaki

Masaaki Kitajima

Toru Masukawa

Keiko Kuribayashi

A process of producing particles for diagnostic reagent, including forming a matrix particle by mixing a nuclear particle having a CV value of 20% or less and a magnetic substance containing at least one of FeOand FeOand giving a shear force to the mixture to adsorb the magnetic substance on the surface of the nuclear particles; and polymerizing a polymerizable monomer in the presence of said matrix particle to form a polymer layer on the magnetic substance layer.

Process for producing particles for diagnostic reagent

A process of producing particles for diagnostic reagent, including a step of polymerizing a polymerizable monomer in the presence of a matrix particle having a magnetic substance layer containing at least one of Fe O and Fe O on the surface thereof and having a mean particle size of 0.4-200 &mgr;m to form a polymer layer on the magnetic substance layer.

A particle for a diagnostic agent, which comprises a polymer particle comprising (A) from 20 to 100% by weight of a structural unit derived from at least one of acrylate having an aliphatic hydrocarbon group and methacrylate having an aliphatic hydrocarbon group, (B) from 0 to 10% by weight of a structural unit derived from unsaturated carboxylic acid, and (C) from 0 to 80% by weight of a structural unit derived from a vinyl monomer copolymerizable with the acrylate, methacrylate and unsaturated carboxylic acid, and a turbidmetric immunoassay using the same.

Particle for diagnostic agent and turbidmetric immunoassay using the same

A hybridization carrier, containing a single-stranded polynucleotide having the formula:

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Tokyo, Japan

Mikio Hikata