University of Cincinnati

Eccrine Systems, Inc.

Mikel Larson

Jason C Heikenfeld

Nicholas Bailey

Michelle Hoffman

Andrew Beckman

Adam Hauke

Brian P Hanley

Robert Beech

Jacob A Bertrand

Gavi Begtrup

Austin Morgan

Eliot Gomez

Isaac Stamper

Jessica Francis

Cory Newland

Devices and methods are described herein for directly and accurately measuring sweat flow rates using miniaturized thermal flow rate sensors. The devices () include the flow rate sensors () in or adjacent to a microfluidic component () of a wearable sweat sensing device. The devices and methods optimize the sensitivity of the flow rate sensors, while minimizing the presence of noise, in order to accurately and directly measure sweat flow rates.

Sweat rate measurement devices

A device for determining the amount or concentration of an analyte in a fluid sample and a flow rate of the fluid sample in a channel is provided. The device includes a chamber including a channel and an opening the channel in fluid communication with the opening. The device further includes a wicking component positioned adjacent to the opening configured to receive an amount of fluid from the channel. The device may further include an analyte sensor positioned on the wicking component, the analyte sensor configured to detect an analyte in fluid in contact with the analyte sensor, wherein the wicking component is configured to contact the amount of fluid with the analyte sensor. Alternatively the device may include at least one pair of electrodes configured to determine a flow rate of the fluid in the channel.

Discrete volume dispensing system flow rate and analyte sensor

Embodiments of the disclosed invention provide devices and methods to incorporate suspension-based, i.e., hydrogel-based and thixotropic compound-based, ion-selective electrodes and reference electrodes into a wearable sweat sensing device. Embodiments of this device are configured to monitor sweat electrolyte concentrations, trends, and ratios under demanding use conditions. The accompanying method includes use of the disclosed device to track fluid and electrolyte gain and loss in order to produce an electrolyte estimate, such as a sweat electrolyte concentration, a sweat electrolyte concentration trend, a sweat rate, or a concentration ratio between a plurality of electrolytes.

Sweat electrolyte loss monitoring devices

Growing community of inventors

Cincinnati, OH, United States of America

Mikel Larson