Jfe Steel Corporation

Daiichi Sankyo Company, Limited

Miho Sato

Makoto Koizumi

Koji Morita

Akitoshi Matsui

Yoshinari Hashimoto

Ryosuke Masuda

Taiga Koriyama

Shugo Morita

Tatsuro Hayashida

An in-mold solidified shell thickness estimation apparatus includes: an input device; a model database configured to store a model formula and a parameter related to a solidification reaction of a molten steel inside a mold of a continuous casting facility; and a heat transfer model calculator configured to estimate an in-mold solidified shell thickness by calculating temperature distributions of the mold and of the molten steel inside the mold by solving a three-dimensional unsteady heat transfer equation. The heat transfer model calculator is configured to correct errors in a temperature of a mold copper plate and in an amount of heat removed from the mold, by correcting an overall heat transfer coefficient between the mold copper plate and the solidified shell.

In-mold solidified shell thickness estimation apparatus, in-mold solidified shell thickness estimation method, and continuous steel casting method

A compound represented by the general formula (III) which serves as an intermediate of an oligonucleotide analog having stable and excellent antisense or antigene activity or having excellent activity as a detection reagent (probe) for a specific gene or as a primer for the initiation of amplification of a specific gene can be produced at high yields regardless of the type of nucleobase by a method comprising reacting a compound represented by the general formula (II) or a salt thereof with a trimethylsilylated compound obtained from a compound represented by the general formula (IVb), wherein X, Y, Z, A, R, and B are as defined in claim

Intermediate for production of nucleoside analog and method for producing the same

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Tokyo, Japan

Miho Sato