Teikoku Seiyaku Co., Ltd.

Toyobo Co., Ltd.

Miho Ishigure

Hideo Isoda

Sadanobu Shirai

Takashi Koida

Masahiro Inazuki

Hiroyuki Sakamoto

Hiroyasu Sakaguchi

Takeshi Ito

The present invention relates to a backing having a three-layer structure prepared by sticking together an inner fiber layer for holding a pasty preparation, a film layer having through-holes, and an air-permeable outer fiber layer which prevents leaking out of the pasty preparation or a liquid component exuded from the pasty preparation, and also relates to an aqueous patch using the backing which can be applied for a long time.

Backing having three-layer structure and aqueous patch using the backing

The present invention relates to a backing for a water-based patch consisting of the following constituents, wherein the backing is excellent in pasty preparation retention and moisture retention, improves the persistence of drug efficacy by inhibiting the sublimation of the drug, gives neither restrained feeling nor rough feeling due to a thin thickness and an excellent elasticity, controls the moisture permeability, gives almost no sticky feeling and thereby gives an excellent feeling in application. A patch backing for a water-based pasty preparation consisting of a laminate, wherein the laminate consists of three layers, a film layer having through-holes is laminated between a nonwoven fabric layer A and a nonwoven fabric layer B, said film layer consists of a resin containing an olefin elastomer, the through-hole area per a hole is 0.02-0.18 mm, and the opening ratio of the through-hole is 1-10%.

Patch backing for water-based pasty preparation

Disclosed is a novel transdermally absorbable preparation which enables the efficient, stable and long-term administration of a drug to a living body. More specifically, the transdermally absorbable preparation comprises: a laminate comprising an outer film, a drug-containing layer and a support layer laminated in this order from the side to be contacted with the skin; and a fixing means for fixing the laminate on the skin. In the transdermally absorbable preparation, the outer film is a drug-permeable polymer film that can control the release of the drug into the skin and is provided as a surface of the laminate which is to be contact with the skin.

Transdermally absorbable preparation

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Higashikagawa, Japan

Miho Ishigure