Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.

Mihaly Nogradi

Sandor Antus

Agnes Gottsegen

Laszlo Feuer

Lorant Farkas

Andras Wolfner

Borbala Vermes

Dezso Korbonits

Lorand Farkas

Janos Strelisky

Gabor Kovacs

Sandor Virag

Jozsef Knoll

Jozsef Szejtli

Gergely Heja

Katalin Marmarosi

Todor Pfliegel

Maria K Toth

Agnes Gettsegen

Borbala Vermes Nee Szluha

Gabor Kovacz

Jozsef Szegi

Agnes Stadler

Janos Streliszky

Zsuzsa Furst

Andreas Wolfner

Maria Kovaks

2,6-di-O-methyl-beta-cyclodextrin complexes of compounds of the formula (1a) ##STR1## wherein R.sup.2' stands for C.sub.1 to C.sub.12 alkyl or a group of the formula ##STR2## in which R.sup.11 is C.sub.1 to C.sub.4 alkyl;

Dibenzo[bd]pyran derivatives, process for the preparation thereof and

The present invention relates to novel 7-substituted benzopyranes of formula (I), wherein

7-Substituted benzopyranes and process for the preparation thereof

An animal feed containing 0.00002 to 0.1% by weight of:

Animal feed containing anabolic isoflavones

Nonestrogenic 5-methyl-alkoxy-isoflavone, namely, 5-methyl-7-methoxy-isoflavone, 5-methyl-7-ethoxy-isoflavone, 5-methyl-7-isopropoxy-isoflavone, and 5-methyl-7-(2-hydroxy-ethoxy)-isoflavone are useful as weight-gain promoters in feeds from which the 7-methoxy and 7-ethoxy isoflavones have been excluded because of estrogenic effects. They are more effective than 7-isopropoxy-isoflavone as well.

Metabolic 5-methyl-isoflavone-derivatives, process for the preparation

Compounds of the formula (1), or their salts, ##STR1## are prepared as follows: (A) A COMPOUND OF THE FORMULA (II) ##STR2## is reduced; or (B) A COMPOUND OF THE FORMULA (III) ##STR3## is reacted, e.g. after protecting the phenolic hydroxy group attached to position 3 of the ring, with a compound of the formula (IV), ##STR4## or (C) GROUP R.sup.1 of a compound of the formula (V) ##STR5## is removed in an acidic medium, AND, IF DESIRED, THE COMPOUND OF THE FORMULA (I) is converted into salt, or a salt of a compound of the formula (I) is converted into the free acid or another salt thereof. The compounds of the formula (I) and their salts are valuable artificial sweetening agents. In the above formulae

Acyl-phenoxy-propanesulfoacids and salts, and artificial sweetening

A sweetening agent in the form of a 1,3-diphenyl-propanone-1 derivative of the formula ##SPC1## Wherein R is hydrogen, hydroxyl, alkoxy or carboxyl-substituted, sulphonyl-substituted, phosphonyl-substituted, dialkylamino-substituted, trialkyl ammonium-substituted alkoxy; R.sup.1 is hydrogen or a hydrophylic group but both R and R.sup.1 are not both hydrogen; R.sup.2 and R.sup.3 are hydroxyl or alkoxy.

1,3-Diphenyl-propanone-1-derivatives and the salts thereof

A method of anabolic treatment in humans comprises administering a compound of the following formula: ##SPC1## Wherein R is halosubstituted, nitrosubstituted, or unsubstituted benzyl, R.sup.2 is hydrogen, methyl or carboxy, and R.sup.3 and R.sup.4 are hydrogen, methoxy or nitro. Pharmaceutical compositions are also disclosed.

Anabolic-weight-gain promoting compositions containing isoflavone

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Budapest, Hungary

Mihaly Nogradi