Politechnika Gdanska

Mieczyslaw Medon

Barbara Wysocka-Skrzela

Czeslaw Radzikowski

Andrzej Ledochowski

Jerzy Gieldanowski

Lucyna Sawinska

Cecylia Kwasniewska-Rokicinska

1-Nitro-9-dialkylaminoisoalkylaminoacridines or their salts of the formula: ##STR1## wherein R is lower alkyl, such as methyl, ethyl, R.sup.1 is a hydrogen atom or methyl, R.sup.2 is the same as R.sup.1, with the proviso that R.sup.1 is not equal to R.sup.2 and n = 0 or 2, and their preparation is described. These compounds are useful as anti-neoplastic agents.

1-Nitro-9-dialkylaminoisoalkylaminoacridines or their salts

1-Nitro-9-alkylaminoalkylaminoacridins and their salts, as well as a method for obtaining these compounds, is described. The 1-nitro-9-alkylaminoalkylaminoacridines have the formula 1, ##STR1## wherein R is methyl, ethyl, propyl, isopropyl, butyl, isobutyl, isopentyl, benzyl or cyclohexyl, whereas n is equal to 2 or 3. The salts are those derived from mineral acids or organic acids. These compounds have anti-neoplastic activity.

1-Nitro-9-alkylaminoalkylaminoacridines and salts thereof

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Mieczyslaw Medon