Robarts Research Institute

University of Washington

Geron Corporation

The University of Western Ontario

Asterias Biotherapeutics, Inc.

Mickie Bhatia

Randall Todd Moon

Jennifer Jean Trowbridge

Anish Sen Majumdar

Joaquin Madrenas

Iris A Ferber

Methods are provided for increasing stem cells, hematopoietic progenitor/stem cells, mesenchymal progenitor/stem cells, mesodermal progenitor/stem cells, muscle progenitor/stem cells, or neural progenitor/stem cells in vivo in a mammalian subject. Methods are also provided for treating an immune related disease, a mesenchymal/mesoderm degenerative disease, or a neurodegenerative disease in a mammalian subject in need thereof.

Methods for regulation of stem cells

This disclosure provides a system for minimizing the alloreactivity of tissue transplants. The patient is administered with undifferentiated embryonic stem cells or early progenitor cells. This induces a state of inflammatory quiescence or immune unresponsiveness, which in turn enhances engraftment of cells derived from the same stem cell line given for purposes of regenerative medicine.

Using undifferentiated embryonic stem cells to control the immune system

Methods and compositions for treating hyperglycemia and pancreatic damage as well as stimulating the repair or regeneration of islet cells are disclosed.

Regeneration initiating cells

Growing community of inventors

London, Canada

Mickie Bhatia