Dsm IP Assets B.v.

Roquette Freres

Dsm IP Assests B.v.

Stichting Dienst Landbouwkundig Onderzoek

Mickel Leonardus August Jansen

René Verwaal

Diana Visser

Rene Verwaal

Laurent Segueilha

Hendrik Martinus Winkelaar

Maarten Job Van De Graaf

Mélanie Louchart

Tania Veiga Dos Inocentes

Joseph Johannes Heijen

Ruud Alexander Weusthuis

Johannes Joseph Heijnen

Ed De Jong

Ronald Hubertus Wilhelmus Maas

The present invention relates to a method for a dicarboxylic acid, which method comprises fermenting fungal cells in a vessel comprising a suitable fermentation medium, wherein a least a portion of the fungal cells are reused in the presence of a vitamin and/or a trace element.

Fermentation process for production of a dicarboxylic acid using fungal cells

The present invention relates to a process for producing a dicarboxylic acid, comprising fermenting a recombinant fungal cell in a suitable fermentation medium, in the presence of high carbon dioxide concentrations.

Dicarboxylic acid fermentation process

The present invention relates to a process for producing a dicarboxylic acid comprising fermenting a fungal cell in a vessel comprising a suitable fermentation medium, comprising adding a gas flow which comprises 20 to 35 v/v % of oxygen and less than 0.1 v/v % of carbon dioxide to the fermentation medium, and maintaining an average partial carbon dioxide pressure of at least about 0.35 bar in the fermentation medium, and producing the dicarboxylic acid.

Process for preparing dicarboxylic acids employing fungal cells

The present invention relates to a process for the production of a dicarboxylic acid and ethanol which comprises fermenting a genetically modified yeast in a suitable fermentation medium under anaerobic conditions at a pH value of between 1 and 5 and producing the dicarboxylic acid and ethanol. The invention also relates to a process for crystallizing succinic acid from an aqueous solution having a pH of between 1 and 5 and comprising succinic acid, comprising removing part of the aqueous solution by evaporation to obtain a concentrated solution, and bringing the temperature of the concentrated solution to a value of between 10 and 30 degrees Celsius, wherein succinic acid crystals are formed.

Dicarboxylic acid production process

The present invention relates to a process for the production of a dicarboxylic acid. The process comprises fermenting a yeast in the presence of a carbohydrate-containing substrate and low amounts of oxygen at a pH value at which at least 50% of the dicarboxylic acid is in the acid form. The process of the present invention allows for high yields of the dicarboxylic acid product and is more cost-effective than existing processes in which the salt is produced which during recovery has to be converted to the acid. It also leads to a simpler and more convenient downstream processing.

Dicarboxylic acid production by fermentation at low pH

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The Hague, Netherlands

Mickel Leonardus August Jansen