Hitachi Medical Corporation

Hitachi, Ltd.

Michiyuki Fujiwara

Atsushi Maki

Fumio Kawaguchi

Masashi Kiguchi

Shingo Kawasaki

Mikihiro Kaga

Tsuyoshi Yamamoto

Hirokazu Atsumori

Noriyoshi Ichikawa

Takashi Ishizuka

Michiyo Tanii

Hideaki Koizumi

Hiroki Sato

Yukiko Hirabayashi

Tsukasa Funane

Tsuneaki Kawaguchi

Hideo Kawaguchi

Takusige Katura

Yukari Yamamoto

Takushige Katsura

Tsuyoshi Takatera

Jacques Mehler

Ghislaine Dehaene-Lambertz

Joerg Schnackenberg

Marcela Pena

Akihiko Toda

The present invention is capable of separating/removing the influence of skin blood flow contained in near infrared spectroscopy (NIRS) signals and extracting a brain- or brain cortex-origin signal. Moreover, the present invention enables versatile separation of brain-origin and skin-origin signals in view of differences among individuals. A biological photometric device, wherein light transmitters and light receivers are located in such a manner that measurement can be conducted at a plurality of source-detector (SD) distances and light received by the individual light-receivers can pass through the gray matter to thereby separate a brain-origin signal and a skin-origin signal. Individual component analysis (ICA) is conducted on data obtained at the individual measurement points. Then, it is determined whether each individual component originates in the brain or in the skin with the use of the SD distance-dependency of the weighted value of each of the separated components.

Biological photometric device and biological photometry method using same

The biological optical measurement instrument is provided with a mobile position sensor that can move in a 3-dimensional space and that detects spatial position in the 3-dimensional space, a head-surface image creating unit that creates a head-surface image of an object and a head-surface point creating unit that creates, on the head-surface image, a head-surface point corresponding to the spatial position of the mobile position sensor.

Biological optical measurement instrument and reference image display method

A biological optical measurement instrument has a gain adjustment unit () configured to set the gain value according to the intensity of the passing light in the measurement data detected by the optical measurement unit (), a gain storage unit () configured to store the damage gain value set by the gain adjustment unit () when a damaged incident optical fiber () or a damaged detection optical fiber () is used, a gain comparison unit () configured to compare the gain value set by the gain adjustment unit () and the damage gain value stored in the gain storage unit (), and a damage determination unit () configured to determine whether or not the incident optical fiber () or the detection optical fiber () is damaged on the basis of the comparison result by the gain comparison unit (). The display unit () displays the damage condition.

Biological optical measurement instrument and method for determining damage of optical fibers

To provide a highly reliable inspection device that prevents a loss in reliability of inspection that uses information from a position detector as a result of the influence of magnetic bodies or the like that are present in the environment, the inspection device includes biological information measurement units that measure biological information of an inspected target and form an image containing the biological information, a magnetic position detector that detects the position of at least one of the biological information measurement units and the inspection target, and a control unit that controls the biological information measurement units and the magnetic position detector; and further includes the control unit being provided with an environmental magnetic field measurement unit that uses the output of the magnetic position detector to measure distortion of the magnetic field in the measured space in which the biological information measurement units are placed.

Magnetic-field measurement jig, magnetic-field measurement program, and inspection device provided with magnetic position detector

A probe holder mounting device for a biological photometric device includes: a probe holder having a plurality of probe mounting parts to which optical fiber probes are mounted; a band-like mounting device body having a plurality of insertion holes into which the probe mounting parts are to be inserted to fix the probe holder in position by means of the insertion holes; belts whose one ends are respectively connected to both longitudinal ends of the mounting device body and whose other ends are engaged with each other; and an adjusting belt connected to the mounting device body at a position where the probe holder is fixed in position in a lateral direction of the mounting device body.

Probe holder mounting device for biological photometric device

There is provided an optical bioinstrumentation device, with which measurement data reflect more correctly the information inside the living body with less noise even the subject moves when the information inside the living body is measured by using the light. In the present invention, the means for fixing the part other than the tips of the optical fibers for irradiation and detection on the fixing member which is to fix the tips of the optical fiber for irradiation and detection on the subject, or, the means for fixing the optical fiber is fixed on the fixing member which is to fix the end of the optical fiber on the subject, or the means for fixing the optical fiber at two or more positions on the subject.

Optical bioinstrumentation devices

A living body information signal processing system () combining organically a living body optical measurement apparatus and a brain wave measurement apparatus, the living body optical measurement apparatus () in which inspection light of from visible to near infrared is irradiated on a head portion of a subject () and the penetration light is received and which measures an optical characteristic variation induced by a brain activity inside the head portion as a living body optical signal and the brain wave measurement apparatus () which measures an electrical characteristic variation induced by a brain activity inside the head portion of the subject as a brain wave signal, is provided with a probe device () used for both apparatus; and a living body information signal processing and displaying device () which displays the living body optical signal corresponding to respective measurement positions from the living body optical measurement apparatus and the brain wave signal corresponding to respective measurement positions from the brain wave measurement apparatus on a common display device while correlating the respective measurement positions each other, thereby, with the system comprehensive observation of both data can be achieved.

Living body information signal processing system combining living body optical measurement apparatus and brain wave measurement apparatus and probe device used for the same

A biological optical measurement instrument including: a measurement probe positionable to a surface of a subject, which irradiates light beams having a plurality of wavelengths from a light beam source through optical fibers onto the subject, and collects the light beams passed inside the subject from a plurality of positions to facilitate production of diagnostics from collected light beams of the subject, wherein the measurement probe is provided with probe casings which hold the optical fibers, fixing members where each respective fixing member is mateable with a respective probe casing to position the probe casings in a predetermined interval, and a support member which supports the fixing members, and wherein at least one of the respective probe casing or the respective fixing member is provided with a stopper claw to permit fixed engagement of the respective probe casing with the respective fixing member upon mating thereof.

Biological optical measurement instrument

In a measuring probe, the distal ends of an irradiation optical fiber and a detection optical fiber on the subject side are held by a holder portion which is to be mounted on a subject. The optical fibers are led out from the side surface of the holder portion. Further, the optical fibers are bent in the holder portion so that the distal ends of the optical fibers are directed towards the subject when the holder portion is mounted on the subject.

Measuring probe and living body optical measuring device

The present invention provides a biological measurement probe readily wearable on a biological surface having a large curvature and a measurement technique of simultaneously measuring the blood circulation dynamic change accompanying the auditory/language/visual function activities of a subject (especially baby) and brain waves. A biological measurement probe having illuminating means for illuminating a subject through a first optical waveguide and light collecting means for collecting light illuminated from the illuminating means and propagated through the subject through a second optical waveguide, has first and second guide members having passages through which the first and second optical waveguides are passed and fixing the first and second optical waveguides, and a base member connecting the first guide member to the second one, holding them, and forming a portion brought into contact with the subject.

Biological measurement probe, biological optical measurement instrument using the same, and brain function measurement instrument

The present invention provides an optical measurement device of biological tissue having a probe attachable to a moving part of a living body with a high curvature in biophotometry. A member having a high flexibility and a high friction coefficient is disposed on a surface for contact with the living body. In addition, a device for light irradiation and a device for collection of light are fixed with an elastic material for uniform pressure application. The resulting double structure or double layer has solved a problem.

Biophotometer

The invention provides a biological photometric device characterized by a method of disposing a light source and a light detector, capable of measuring a distribution of concentrations at different depths and changes in the concentration in the case of measuring and forming an image of the concentration of metabolites in an organ and changes in the concentration. The light sources and light detectors are disposed on the subject so that, in the case of measuring a concentration of metabolites in an organ and changes in the concentration in a shallow portion in the subject by using an about midpoint position between each of the light sources and each of the light detectors as a sampling point, measurement is performed by using a sampling point of a pair of the light source and said light detector which are disposed at a small interval. In the case of measurement in a deep portion in the subject, a sampling point of a pair of the light source and the light detector which are disposed at a large interval is used.

Biological photometric device

A biological optical measuring instrument comprising a measuring probe () for collecting light from a plurality of portions of a subject () transmitted through the subject () by means of an optical fiber () by guiding light emitted from a light source () by an optical fiber (), and irradiating the light to the subject () so as to create a living body transmitted light intensity image of the subject () from the transmitted and collected light. The measuring probe () further comprises optical fiber fixing members () for fixing the optical fibers () at a predetermined interval and support members () for rockably supporting the optical fiber fixing members. Thus, it is possible to provide a technique of performing living body optical measurement while the living body lies in lateral decubitus.

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Kashiwa, Japan

Michiyuki Fujiwara