Other

Yamasa Shoyu Kabushiki Kaisha

Kaken Chemical Co., Ltd.

Yamasu Shoyu Kabushiki Kaisha

Kakenyaku Kako Kabushiki Kaisha

Michio Ui

Motoyuki Yajima

Chikanori Tomioka

Koichi Hosoda

Tsutomu Nakamura

Shigeki Kurokawa

Akira Kuninaka

Katsumi Nogimori

Taira Okamoto

Akio Terashima

Tomokazu Sato

Miyuki Honma

Yukiko Tokumitsu

Isamu Takahashi

Tomokazu Satoh

Yoshinori Kanbayashi

Junichi Takezawa

Akira Ito

A novel biologically active substance named Islets-Activating Protein obtained from the cultivation of the miocroorganism Bordetella and having insulin secretion promoting action as well as glucose tolerance improving action for mammals.

Biologically active substance

A method of quantative determination of adenosine by means, of competitive immunoassay based on a competitive antigen-antibody reaction. In the competitive antigen-antibody reaction, an antibody is used which is obtained from an animal which has been immunized by introduction thereto of an antigen which comprises a carrier protein bonded with 2'- and 3'-hydroxyls of the adenosine through dicarboxylic acid residues, and a labelled adenosine and 2',3'-diacyladenosine which has been produced by acylation of adenosine in the sample to be assayed or in a standard solution are caused to undergo competitive reaction for the antibody whereby it has been made possible to determine adenosine quantitatively in high sensitivity and in high accuracy.

Determination of adenosine by immunoassay involving acylation of the

Novel biologically active substances prepared by dissociating the protein obtained from the cultivation of the microorganism Bordetella and having insulin secretion promoting action as well as glucose tolerance improving action for mammals.

Proteinic active substances

Process for ultramicro-quantitative determination of acetone comprising (1) reacting radioactive molecular or cationic iodine with the acetone contained in a sample from biological preparations in a strong alkaline solution to produce radioactive iodoform according to a haloform reaction quantitatively, (2) reducing the non-reacted molecular or cationic radioactive iodine to a radioactive iodide, (3) separating the radioactive iodoform from the radioactive iodide, and (4) measuring the radioactivity of the radioactive iodoform by any conventional method. Two types of assay kits suitable for use in this determination of acetone comprise respectively:

Ultramicro-quantitative determination of acetone and kit suitable

An assay kit for assaying adenosine-3',5'-cyclic monophosphate, which is herein referred to as cAMP, guanosine-3',5'-cyclic monophosphate, which is herein referred to as a cGMP, or both; and said assay kit comprising,

Assay kit for cAMP and/or cGMP and method of using the same

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Sapporo, Japan

Michio Ui