The Furukawa Electric Co., Ltd.

The University of Tokushima

Mitsui Chemicals, Inc.

Keio University

The Furukawa Battery Co., Ltd.

Michio Ohkubo

Hideki Aizawa

Akihiko Kasukawa

Yoshikazu Ikegami

Kazutomi Miyoshi

Yutaka Ohki

Takeshi Namegaya

Nobumitsu Yamanaka

Keiichi Yabusaki

Masataka Nishida

Hiroshi Matsuura

Toshio Tani

Naoki Uno

Michihiro Shimada

Michihiro Nakamura

Takao Ninomiya

Takeshi Shiojima

Hirokazu Miyoshi

Yosuke Hirayama

Takeshi Yagi

Hitoshi Shimizu

Junji Yoshida

Takeshi B Nishimura

Norihiro Iwai

Kunihiro Noda

Takuya Ishikawa

Daisuke Saito

Masayuki Fukushima

Kiyofumi Muro

Satoshi Arakawa

Tsuyoshi Fujimoto

Takeharu Yamaguchi

Tomohiro Takagi

Toshio Kikuta

Hidetoshi Abe

Tetsuhiko Isobe

Satoru Okada

Takeshi Koiso

Tetsuro Ijichi

Atsushi Ohkubo

Miyu Aita

Ryo Asakura

Silica particles having a thiol group on a surface thereof, and satisfying the following conditions (a) to (c):

Silica particles having reactive functional group on surface, and method of producing the same

A method of producing a labeled antibody, including the steps of:

Method of producing labeled antibody

Labelled silica nanoparticles for immunochromatographic reagent, comprising silica nanoparticles containing a labelled substance.

Labelled silica nanoparticles for immunochromatographic reagent, immunochromatographic test strip using the same, and immunochromomatographic fluorescence-detecting system or radiation-detecting system

A method of detecting a target substance, containing the steps of:

Method of detecting target substance

An immunochromatography for multi-item detection is provided which contains detecting and measuring fluorescence and light absorption respectively at once with a detection device. The immunochromatography contains using fluorescent particles and light absorbing particles, wherein the fluorescence excitation wavelength of the fluorescent particles and the absorption wavelength of the light absorbing particles are in the same wavelength region; and detecting and measuring, at once, the intensity of reflected light from a test area, the intensity of reflected light from another test area, and the intensity of reflected light from a non-test area other than the test areas.

Immunochromatography, and detection device and reagent for the same

The invention is directed to a fluorescence immunochromatography method carried out by illuminating a fluorescent substance in a membrane with excitation light and detecting fluorescence emitted from the fluorescent substance, by applying a sample to a test strip having a membrane and a transparent film attached to the surface of the membrane, wherein the transparent film satisfies Formula (1) Formula (1) n&#x3e;n(n: refractive index of transparent film at wavelength &#x3bb;of the fluorescence) (n: refractive index of analyte liquid at wavelength &#x3bb;of the fluorescence), and wherein the membrane contains a fluorescent labeling reagent which binds to target substance contained in the sample; binding the fluorescent labeling reagent to the target substance; immobilizing the fluorescent labeling reagent bound to the target substance in the membrane; detecting the presence of target substance.

Fluorescence immuno-chromatography, kit and test strip for the same

Colloidal silica particles containing a fluorescent dye compound, composed of a silica particle containing a silica component and a fluorescent dye compound chemically bound or adsorbed thereto, wherein the colloidal silica particles containing a fluorescent dye compound have an average diameter of 30 nm or less, and wherein said silica particles are used simultaneously as fluorescent-labelling nanobeads; a fluorescent nano-material comprising said colloidal silica particles; and a biochip and an assay method using the same.

Fluorescent silica nano-particle, fluorescent nano-material, and biochip and assay using the same

An object of the present invention is to provide a cathode active material which contains small-particle sized and low-crystalline lithium transition metal silicate and which undergoes charge-discharge reaction at room temperature. The cathode active material for a non-aqueous electrolyte secondary battery is characterized by containing a lithium transition metal silicate and exhibits diffraction peaks having half widths of 0.175 to 0.6&#xb0;, the peaks observed through powder X-ray diffractometry within a 2&#x3b8; range of 5 to 50&#xb0;.

Cathode active material, cathode, secondary battery and manufacturing methods for the same

A method of producing functional molecule-containing silica nanoparticles on which a biomolecule is bonded, containing the steps of:

Method of producing functional molecule-containing silica nanoparticles on which biomolecules are bonded

A system of quantitatively determining a biomolecule, which has: allowing fluorescent silica particles capable of emitting fluorescence detectable by a flow cytometer to capture a target biomolecule fluorescent-labelled for quantitative determination; detecting the fluorescence emitted from the fluorescent silica particles themselves by using the flow cytometer; and measuring the intensity of the fluorescence of the labelled target biomolecule, thereby quantitatively determining the target biomolecule.

System and method of quantitatively determining a biomolecule, system and method of detecting and separating a cell by flow cytometry, and fluorescent silica particles for use in the same, and kit comprising plural kinds of the silica particles in combination

A particulate mixture which can be used as a precursor of lithium transition metal silicate-type compound of small particle size and low crystallinity, is provided. It is a mixture of silicon oxide particulates, transition metal oxide particulates, and lithium transition metal silicate particulates, and its powder X-ray diffraction measurement shows diffraction peaks near 2&#x3b8;=33.1&#xb0; and near 2&#x3b8;=35.7&#xb0;, and said silicon oxide particulates and said transition metal oxide particulates are amorphous, and said lithium transition metal silicate particulates are in a microcrystalline or amorphous state.

Particulate mixture, active material aggregate, cathode active material, cathode, secondary battery and methods for producing the same

Labelled silica nanoparticles for immunochromatographic assays

A colloidal silica particle containing a light-absorbing substance, comprising a colloidal silica particle and a light-absorbing substance distributed over the colloidal silica particle, wherein the light-absorbing substance is chemically bound to or adsorbed on a silica component.

Colloidal silica particle containing light-absorbing substance, nano light-absorbing material, absorption labeling nanobead kit, and method for detection or quantification of biological molecule using the colloidal silica particle containing light-absorbing substance

A fluorescent labeling reagent of the present invention includes an inorganic fluorescent particle and a material (A) having a material (B) of biological origin adsorbed or bound thereto. The inorganic fluorescent particle is integrated with the material (A) so as to form the reagent of the present invention. The inorganic fluorescent particle used in the present invention is capable of emitting light with a wavelength of 650 nm to 1600 nm in the infrared region or the near-infrared region which can be detected by means of Si&#x2014;CCD or InGaAs&#x2014;PD and can penetrate an HO rich sample when excited by light with a wavelength of 650 nm or longer which has the shortest transparent wavelength of AlInGaP-LD including oxygen adsorption type hemoglobin used for DVDs etc.

Fluorescent labeling reagent

A wavelength conversion module according to the present invention includes an external resonator, a semiconductor laser module and a wavelength conversion device for converting a wavelength of light output from the semiconductor laser module into a shorter wavelength. This wavelength conversion device includes at least one of a nonlinear crystal for generating SFG (Sum-frequency Generation) light and a nonlinear crystal for generating SHG (Second Harmonic Generation) light. Each of the SFG generating element and the SHG generating element of the wavelength conversion device may have a periodically-poled ridge-waveguide structure or a periodically-poled proton-exchanged-waveguide structure.

Wavelength conversion module

Growing community of inventors

Tokyo, Japan

Michio Ohkubo