Pola Chemical Industries, Inc.

Michio Ochiai

Hiromichi Sagitani

Kenichi Goto

Yoshihiro Tokudome

Shigenari Hirokawa

Noriaki Tonooka

Kenkichi Matubara

Yoshihiro c/o Pola Chemical Industries Inc Tokudome

In a triterpenic acid having hydroxyl groups, at least one of the hydroxyl groups is phosphorylated to produce a phosphorylated triterpenic acid and/or a salt thereof, thereby improving the solubility of the triterpenic acid in a preparation for external application for the skin and allowing the physiological activity of the triterpenic acid to be exerted satisfactorily. The phosphorylated triterpenic acid is preferably, for example, ursolic acid phosphate and/or a salt thereof. The preparation for external application for the skin is preferably a cosmetic, particularly preferably a quasi-drug.

Triterpenic acid derivative and preparation for external application for skin comprising the same

A hydrophilic cosmetic product contains a novel randomly polymerized polyglycerol, polytrimethylene- or -tetramethylene-oxide condensate of an 8-36 carbon aliphatic alcohol or fatty acid useful as a non-ionic surface active agent.

Polyglycerol compounds and cosmetic products containing the same

A novel randomly polymerized polyglycerol, polytrimethylene- or -tetramethylene-oxide condensate of an 8-36 carbon aliphatic alcohol or fatty acid useful as a non-ionic surface active agent.

Disclosed are cosmetics containing an oily bisdiglyceryl ether compound. This novel compound can be prepared by adding an alkylene glycol, dialkylene glycol, trialkylene glycol or tetraalkylene glycol dropwise to an alkylglycidyl ether using as a catalyst a boron trifluoride ether complex, other Lewis acid, sodium hydroxide or potassium hydroxide and removing the catalyst with the use of sodium carbonate, calcium carbonate, potassium carbonate, these aqueous solutions or water upon heating, followed by rectification of the resultant oily liquid under reduced pressures. The cosmetics of this type do not cause any dermatitis or skin disease due to the absence of surface active agents.

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Yokohama, Japan

Michio Ochiai