Kyoto Daiichi Kagaku Co., Ltd.

Arkray, Inc.

Kurashiki Boseki Kabushiki Kaisha

Kabushiki Kaisha Kyoto Daiichi Kagaku

Michio Naka

Kouji Hirayama

Hisashi Okuda

Yoshihiko Higuchi

Masufumi Koike

Yasunori Shiraki

Daisuke Matsumoto

Kexin Xu

Masafumi Koike

Norihito Suzuki

The present invention relates to a microchiphaving a translucent member, a flow channelor a cell formed at a side of the translucent memberwhere light enters, and an apertureformed at a position corresponding to the flow channelor the cell at a side of a translucent memberwhere light goes out. The aperturehas a light go-through surfacewhich causes light flux being emitted from the flow channelor the cell to go through and a light reflective surfacethat totally reflects the incident light flux. A width size Wof the light go-through surfaceis smaller than a width size Wof the flow channelor the cell.

Microchip and analyzing apparatus

A suction generating device for a sample analysis device is provided. The device comprises four parts, namely, a cover plate, a middle plate, a bottom plateand an operation plate. A protruding portionfor compressing the suction generating chamber is formed in an approximately center portion on the lower side of the operation plate, a protruding portionfor operation is formed in an approximately center portion on the upper side of the operation plate. A cavityfor inserting the sample analysis device therein is formed in an approximately center portion in the bottom plate; and a holefor light irradiation is punched in a determined portion in the cavity. A concave portionfor fitting the operation platetherein is formed in the middle plate, and a window sectionis formed in the center of the concave portionto let the lower protruding portionon the operation plateprotrude therethrough. A window sectionis formed in the cover plateto let the upper protruding portionon the operation plateprotrude therethrough.

Device for analyzing a sample

A suction generating device for a sample analysis device is provided. The device comprises four parts, namely, a cover plate,a middle plate,a bottom plate,and an operation plate,A protruding portion,for compressing the suction generating chamber is formed in an approximately center portion on the lower side of the operation plate,a protruding portion,for operation is formed in an approximately center portion on the upper side of the operation plate,A cavity,for inserting the sample analysis device therein is formed in an approximately center portion in the bottom plate,and a hole,for light irradiation is punched in a determined portion in the cavity,A concave portion,for fitting the operation plate,therein is formed in the middle plate,and a window section,is formed in the center of the concave portion,to let the lower protruding portion,on the operation plate,protrude therethrough. A window section,is formed in the cover plate,to let the upper protruding portion,on the operation plate,protrude therethrough.

Suction generating device and sample analysis apparatus using the same

A test apparatus for assaying a component in a liquid sample by measuring a reflected light, comprising a support having a through hole or a light permeable area, a reagent layer having a detecting area fixed on the support to cover said through hole or light permeable area, and a cover which covers at least the detecting area, wherein at least a portion of the cover covering the detecting area is of a color which substantially has no influence on the reflected light at a measured wavelength.

Test apparatus for assaying a component in a liquid sample

This invention provides a device for analyzing a sample which is capable of performing rapid and precise analysis of a small amount of sample, and whose gradient in a measuring apparatus is not limited. This device comprises approximately a rectangular plate shaped body comprising a base member made of resin and a transparent covering. A first depressed cylindrical concave portion is formed in the upper surface of the base member, and a groove is formed in communication with the first depressed cylindrical concave portion, the groove extending to the end of the protrusion portion,, and a second depressed cylindrical concave portion which is smaller than the first depressed cylindrical concave portion is formed in a certain position in the groove, the end of the groove opening to the outside at the end of the protrusion portion,. Then, the transparent covering is placed over the upper surface of the base member and then integrated together. As a result, the first depressed cylindrical concave portion, the groove, the second depressed cylindrical concave portion, and the opening at the end of the groove are formed into a suction pressure generating chamber, a drawing channel, an analytical section, and an opening for drawing a sample, respectively.

A method of and a device for accurately positioning a measuring means such as a measurement probe relative to that target area of a living body which has a unique marking peculiar to the living body. A transparent sheet member is first applied to the target part, and an image of the unique marking is then transferred onto the transparent sheet member. The transparent sheet member bearing the image of the unique marking is associated with the measuring device so that a subsequent measurement can be performed by the measuring device after the image transferred onto the transparent sheet member has been aligned with the unique marking in the target area.

Probe positioning method and device therefor

This invention provides a device for analyzing a sample which is capable of performing rapid and precise analysis of a small amount of sample, and whose gradient in a measuring apparatus is not limited. This device comprises approximately a rectangular plate shaped body comprising a base member made of resin and a transparent covering. A first depressed cylindrical concave portion is formed in the upper surface of the base member, and a groove is formed in communication with the first depressed cylindrical concave portion, the groove extending to the end of the protrusion portion 5c, and a second depressed cylindrical concave portion which is smaller than the first depressed cylindrical concave portion is formed in a certain position in the groove, the end of the groove opening to the outside at the end of the protrusion portion 5c. Then, the transparent covering is placed over the upper surface of the base member and then integrated together. As a result, the first depressed cylindrical concave portion, the groove, the second depressed cylindrical concave portion, and the opening at the end of the groove are formed into a suction pressure generating chamber, a drawing channel, an analytical section, and an opening for drawing a sample, respectively.

An optical analyzer includes a light emitting diode (LED). The LED has a body pervious to light and a PN junction semiconductor. The body has a surface portion where a primary light emitted from semiconductor is divided into a first light and a second light. The first light is reflected at a sample and then received by a first detector, while the second light is detected by a second detector. An optical property of the sample is determined by the use of outputs of the first and second detectors.

Optical system and light emitting diode having a light dividing surface

The optical measuring apparatus of this invention for measuring a physical amount of a specific component contained in a substance to be measured by the use of measurement light which passes through the substance to be measured and the use of predetermined reference light includes: a first interfering polarizing plate for obtaining a first light interference signal by interfering the measurement light; a second interfering polarizing plate for obtaining a second light interference signal by interfering the reference light; a first photoelectric converting section for converting the first light interference signal into a first electric signal; a second photoelectric converting section for converting the second light interference signal into a second electric signal; a first phase expanding section for expanding a phase of the first electric signal; a second phase expanding section for expanding a phase of the second electric signal; a phase difference measuring section for measuring a phase difference between a phase expanded by the first phase expanding section and a phase expanded by the second phase expanding section; and a physical amount determining section for determining the physical amount of the specific component contained in the substance to be measured depending on the phase difference measured by the phase difference measuring section.

Apparatus/method for optical measuring a physical amount of a specific

A number of blood samples collected in sample vessels are allowed to stand by as whole blood or blood cell layer, the sample vessels are sent into sampling part in order, the blood sample suctioned from the sampling nozzle is diluted by mixing with hemolyzing liquid containing labile HbA.sub.1c removing reagent, a part of the mixture is led to a sample-loop of sample injection valve and injected into the column of high pressure liquid chromatograph at a specified time after mixing start, hemoglobin fractions are measured in the state of removal or lowering of labile HbA.sub.1c, and the rate of stable glycohemoglobin is determined from thus obtained chromatogram.

Growing community of inventors

Kyoto, Japan

Michio Naka