Nippon Telegraph and Telephone Corporation

Ntt Corporation

Toray Industries, Inc.

Michiko Seyama

Toru Miura

Tsutomu Horiuchi

Yuzuru Iwasaki

Yujiro Tanaka

Daichi Matsunaga

Tsuneyuki Haga

Tsuyoshi Hayashi

Jun-ichi Takahashi

Masahito Nakamura

Serge Camou

Yasuhiro Sato

Takako Ishihara

Kazuhiko Takagahara

Ryusuke Kawano

Jyunichi Takahashi

Hiroshi Koizumi

Masanobu Sato

Ryoichi Kasahara

Shingo Tsukada

Nobuaki Matsuura

Kei Kuwabara

Takayuki Ogasawara

Nahoko Kasai

Kazuyoshi Ono

Emiko Ishikawa

Takuro Tajima

Keiji Takeda

Koji Sumitomo

Noriko Nagai

Katsuyoshi Hayashi

Atsushi Horiuchi

Katsuhiro Ajito

Jun-Ichi Takahashi

A pressurizing unit applies pressure around a measurement site of a measurement subject so as to suppress blood flow at the measurement site during a set pressurizing time. While the pressurizing unit is applying pressure around the measurement site, a detection unit detects a photoacoustic signal generated at the measurement site irradiated with a light beam. The detection unit detects a photoacoustic signal when a preset time has elapsed after the pressurizing unit started to apply pressure around the measurement site.

Method and device for measuring concentration of component

A dielectric spectroscopy measuring device includes a signal generation unit that generates electromagnetic waves, a signal separation unit that separate the electromagnetic waves according to a transmission direction and outputs the separated electromagnetic waves to an output destination corresponding to the transmission direction, a changeover switch unit that receives the electromagnetic waves generated by the signal generation unit via the signal separation unit, switches an output destination, and outputs the received electromagnetic waves, and outputs electromagnetic waves returning from the output destination to the signal separation unit, a sensor unit that irradiates a measurement target with the electromagnetic waves output by the changeover switch unit, and outputs measurement target waves obtained by irradiation to the changeover switch unit, a calibration standard unit including a circuit for calibration standard, the circuit outputting reflected waves for calibration generated by receiving the electromagnetic waves output by the changeover switch unit to the changeover switch unit, a signal reception unit that receives the measurement target waves and the reflected waves for calibration via the signal separation unit, and an operation unit that receives a measurement value output by the signal reception unit receiving the measurement target waves and the reflected waves for calibration, and corrects the received measurement value of the measurement target on the basis of the measurement value corresponding to the received reflected waves for calibration.

Dielectric spectroscopy measuring device and dielectric spectroscopy measuring method

A light emitting unit irradiates a measurement site of a measurement subject with a light beam having a wavelength that is absorbed by a measurement target substance. A detection unit detects a photoacoustic signal generated in the measurement site irradiated with the light beam emitted from the light emitting unit. A resonator is arranged so as to clamp the measurement site, and causes the above-described photoacoustic signal to resonate. The resonator is constituted by a first reflection unit and a second reflection unit. The first reflection unit is arranged between the light irradiation unit and the measurement site. Also, the light beam passes through the first reflection unit. The second reflection unit is arranged between the detection unit and the measurement site.

Component concentration measuring device

A temperature measurement device includes a first probe that measures a physical quantity related to a temperature of a substance on the basis of a first reference, a second probe that measures a physical quantity related to a temperature of the substance on the basis of a second reference different from the first reference, and a heat conductive member that covers the first probe and the second probe and transports heat from the substance.

Temperature measurement device and temperature measurement method

A suction channel is made of a flexible resin, and is formed in a base. The suction channel suctions sweat that has come into contact with the detection electrode. The suction channel makes use of surface tension from micro channels to suction liquid into an interior from a suction port. A sodium ion detection electrode, a potassium ion detection electrode, and a reference electrode, which are detection electrodes for detecting ions contained in the sweat, are formed on an inner wall of a channel of the suction channel.

Wearable sensing device

An internal temperature measurement device includes a sound wave sensor that transmits a sound wave to a subject and receives a reflected sound wave reflected by the subject, a time measurement device that measures an elapsed time elapsed between transmission of the sound wave from the sound wave sensor and reception of the reflected sound wave, a sound velocity calculator that calculates a sound velocity in the subject according to the elapsed time measured by the time measurement device, and an internal temperature derivation device that determines an internal temperature of the subject according to the sound velocity calculated by the sound velocity calculator.

Internal temperature measurement device and method

A device includes: an ultrasonic wave irradiation unit that irradiates a living body with an ultrasonic wave; an ultrasonic wave detection unit that receives an ultrasonic wave reflected by the living body; and a calculation unit that calculates an amount of temperature change in the living body. The calculation unit is configured to: calculate a frequency of an ultrasonic wave amplified in the living body, based on information on a structure of the living body; perform frequency analysis on the ultrasonic wave received by the ultrasonic wave detection unit and acquire an amplitude spectrum of the ultrasonic wave; identify, from the amplitude spectrum, a peak frequency closest to the frequency of the ultrasonic wave; calculate an amount of frequency change, from two peak frequencies identified by ultrasonic wave irradiations in twice; and calculate an amount of temperature change in the living body from the amount of frequency change.

Living body internal temperature measuring device

A heat flux sensor including two temperature sensors is used to obtain time-series data of a core temperature of a living body, and a blood flow rate in a vicinity of the heat flux sensor is measured by a blood flow sensor. In an arithmetic circuit, a delay time until a fluctuation of the core temperature of the living body is reflected on an epidermis temperature is calculated on the basis of the blood flow rate measured by the blood flow sensor and a previously prepared relation between the blood flow rate and the delay time until the fluctuation of the core temperature of the living body is reflected on the epidermis temperature, and a time corresponding to the core temperature of the living body on the basis of the delay time is corrected.

Living body internal temperature measuring device and living body internal temperature measuring method

A light irradiation unit configured to irradiate a measurement part with a light beam that has a wavelength absorbed by glucose and a detection unit configured to detect a photoacoustic signal generated from the measurement part irradiated with the light beam emitted from the light irradiation unit are included. The light irradiation unit irradiates the measurement part by scanning the light beam 2-dimensionally. The measurement part is irradiated with the light beam through raster scanning. For example, the light beam has a beam diameter of about 100 μm and is scanned at a scanning speed of about 100 μm/10 ms.

Component concentration measurement device

An in-vivo temperature measurement device includes a plurality of thermal resistors, temperature sensors for measuring an epidermis temperature of a living body, and temperature sensors for measuring an upper surface temperature that are provided at both ends of the thermal resistors, respectively, a memory that stores an estimation model of the core temperature of the living body that takes into consideration a non-thermal equilibrium state of the living body, and thermal resistance values of the thermal resistors, and an arithmetic circuit that estimates, based on the plurality of temperatures measured by the temperature sensors and the temperature sensors, the core temperature of the living body using the estimation model and the thermal resistance values, and the thermal resistance values are different from one another.

Internal body temperature measurement device and internal body temperature measurement method

A component concentration measuring apparatus includes: a dielectric spectroscopy portion that irradiates a measurement subject with electromagnetic waves and measures a complex permittivity, thereby acquiring a dielectric spectroscopy spectrum; a temperature measurement portion that measures a temperature of the measurement subject; a signal processing portion that corrects the dielectric spectroscopy spectrum according to the temperature measured by the temperature measurement portion; and a calculating portion that applies a calibration model generated in advance from a dielectric spectroscopy spectrum of a sample whose component concentration is known, to the dielectric spectroscopy spectrum corrected by the signal processing portion, thereby calculating a component concentration of the measurement subject. A dielectric spectroscopy sensor that transmits and receives electromagnetic waves and a temperature sensor that outputs a signal that changes in accordance with a temperature are fixed to the measurement probe such that a certain distance is interposed between the sensors.

Component concentration measurement device and component concentration measurement method

In a biological signal measurement system of this invention, biological digital data is generated from a biological signal measured by a biological signal measurement apparatus, and first feature amount data extracted from the biological digital data and downsized biological digital data are transmitted to a portable terminal. In a biological information measurement apparatus of this invention, biological feature amount data is extracted from measured biological waveform data, and at least one of the biological waveform data and the biological feature amount data is transmitted to an external device. It is possible to provide a biological signal measurement system capable of continuously measuring a biological signal for a long time without disturbing daily life and provide a biological information measurement apparatus capable of implementing downsizing and long life of a battery.

Biological signal measurement system, biological information measurement apparatus, and biological information extraction algorithm changing method

A bioelectrode includes a fitting member () formed by an electrically insulating member fixed on a surface of a garment () that comes in contact with a living body (), an electrode part () formed by a conductive member fixed on a surface of the fitting member () that comes in contact with the living body (), a connector () fixed to the fitting member () and configured to connect a bioelectric signal measurement device, a wiring line () fixed to the fitting member () and configured to electrically connect the connector () and the electrode part (), and an electrically-insulating insulating member () configured to cover a portion within the surface of the wiring line () that comes in contact with the living body ().

Bioelectrode and garment

A flow rate measurement apparatus includes a light oscillator; a thin metallic film which causes surface plasmon resonance by light output from the light oscillator; a focusing unit which fixes the thin metallic film and converts the output light of the light oscillator into incident light having a plurality of incident angles to focus the incident light at a location of a focal line in a straight line shape on the thin metallic film; a measurement part having antibody fixed areas to which an antibody is fixed and reference areas to which an antibody is not fixed, the antibody fixed areas and the reference areas being alternately arranged at a location along the focal line location on the thin metallic film; a light receiver which receives reflected light, at the focal line location, of the output light by surface plasmon resonance occurring at the focal line location, at each of the plurality of incident light angles; an SPR angle calculator which obtains a temporal change of an SPR angle in each of the antibody fixed areas and the reference areas in the measurement part; and a flow rate operation unit which calculates the flow rate of the sample flowing in the flow cell based on the temporal change of the SPR angle obtained by the SPR angle calculator.

Flow rate measurement apparatus, antigen concentration measurement apparatus, flow cell, flow rate measurement method, and antigen concentration measurement method

An object of the present invention is to provide an element for SPR measurement without the need of a mechanical solution-sending mechanism. The scope of the present invention is defined by a sensor element for surface plasmon resonance (SPR) measurement utilizing an SPR effect, wherein the sensor element comprises a transparent substrate, a gold thin film formed on at least a part of the transparent substrate, and a thin film with affinity for a sample provided on the transparent substrate having the gold thin film formed on at least a part thereof, and the thin film with affinity for a sample has a measurement region (region A), a sample introduction section (region B) and a sample absorption section (region C) provided with the region A therebetween, the region A is provided with a sample measurement section containing a molecule-recognizing film, an introduction port is formed on the film with affinity for a sample in the region B, an absorption pad is provided on the film with affinity for a sample in the region C so that the whole region C should be covered, and a point in the region B, a point in the region A, and a point in the region C exist in one straight line on the thin film with affinity for a sample.

Growing community of inventors

Tokyo, Japan

Michiko Seyama