Kao Corporation

Michihiro Hattori

Genji Imokawa

Naotake Takaishi

Koichi Nakamura

Shuichi Akazaki

Toru Tejima

Akira Kawamata

Kimihiko Hori

Shinji Yano

Tadashi Tamura

Shinichi Masuda

Naonobu Yoshizuka

Hajime Hotta

Tohru Tejima

Novel cosmetic compositions comprising a lipid derived from horny cells can enhance a moisture retention ability of the horny layer and are useful for remedy of dry skin. When the lipid is used in combination with surface active agents, the above effect is enhanced. The cosmetic compositions may take any preparations such as creams, milky lotions, beauty wash, rouges, foundations, hair tonics and the like.

Cosmetic compositions

An external medicament comprises a novel amide derivative represented by the following formula (I). ##STR1## The external medicament is applicable to both a pharmaceutical external medicament and a cosmetic composition, and it provides excellent improving and preventing effects for chapping of the skin.

Amide derivative and external medicament comprising same

A composition for application to the skin to protect the skin from the long wavelength ultraviolet ray comprises a dibenzoylmethane derivative of the following general formula ##STR1## in which X represents a hydrogen atom, a monovalent metal cation, an organic cation, a linear or branched alkyl group having from 1 to 24 carbon atoms, or a polyoxyalkylene oxide having 2 or 3 carbon atoms, Y and Z each independently represent a hydroxyl group, a linear or branched alkyl group having from 1 to 24 carbon atoms, or an alkoxy group having from 1 to 24 carbon atoms, or a polyoxyalkylene oxide group having from 2 to 3 carbon atoms, and m and n are independently an integer of from 0 to 3. The composition is adjustable so as to have an optimum HLB balance and has good compatibility with various cosmetic bases. Further, it does not irritate the skin, is difficult to be percutaneously absorbed and shows continued skin-protecting effects.

Long wavelength ultraviolet ray absorber

4-methoxy-2'-carboxydibenzoylmethane of the following general formula (I) ##STR1## is prepared by reacting p-methoxyacetophenone (III) with phthalic anhydride (II) in accordance with the following reaction equation. ##STR2##

4-methoxy-2'-carboxydibenzoylmethane and its salts

A chalcone derivative of the formula (I): ##STR1## in which R.sub.1 represents hydrogen or a methyl group, and R.sub.2 represents a linear or branched aliphatic hydrocarbon group having from 2 to 24 carbon atoms. The derivative is effective in protecting the skin when made into ultraviolet absorbing agents including an anti-sunburn oil, since it has the maximum absorbing capacity at a wave length in the vicinity of 350 nm, does not irritate the skin and is highly compatible with a cosmetic base.

Novel chalcone derivatives and ultraviolet absorbers comprising the same

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Utsunomiya, Japan

Michihiro Hattori