Otsuka Pharmaceutical Company, Limited

Michiharu Sugawara

Takashi Kamogashira

Tsutomu Nishida

Setsuko Takegata

Yoshimasa Nakano

Taketoshi Izawa

Tomoyuki Kawaguchi

Setsuyoshi Uetsuki

Tomiyo Nihno

Akira Wada

A novel pyrazinoxide compound of NF-1616-904 having the formula (1), ##STR1## prepared by hydrolyzing the intermediate compound of NF-1616-902 which is separated from a culture broth of a microorganism belonging to the genus Thielavia. The pyazinoxide compound of NF-1616-904 possess biological and pharmacological activities, and is useful agent for preventing and treating diseases caused by superoxide radicals (O.sub.2.sup.-), and nephritis.

Novel pyrazinoxide compound of NF-1616-904 and a pharmaceutical

OA-7653 Substance

A process for producing an antibiotic Cephamycin C which comprises cultivating a strain of Streptomyces sp. OFR 1022 in a culture medium to accumulate therein Cephamycin C and recovering said Cephamycin C.

Process for the production of antibiotic Cephamycin C

Growing community of inventors

Tokushima, Japan

Michiharu Sugawara