Green Tech Co., Ltd.

Kyoto University

Tokyo Institute of Technology

Michiaki Okuda

Hachiro Sugimoto

Shinichi Nakayama

Takashi Takahashi

Yoshikazu Inoue

Ichiro Hijikuro

Rie Tokizane

Yoko Sakata

Yuki Fujita

Hidetaka Suzuki

Provided is a novel therapeutic means for Alzheimer's disease. In particular, provided is a compound represented by the following general formula (I): ora salt thereof.

Pyrazole derivative

Provided is a novel therapeutic means for Alzheimer's disease. In particular, provided is a compound represented by the following general formula (I): [wherein Arrepresents 2-methoxy-4-(2-pyridylmethoxy)phenyl etc. and Arrepresents a 1H-indol-6-yl group etc.] or a salt thereof.

To develop a highly safe measure to treat Alzheimer's disease using a secretase-inhibiting substance, there is provided a compound represented by the following general formula (I) or a salt thereof: wherein A represents a phenyl group or the like, Rrepresents a chlorine atom, a bromine atom, or a nitro group or the like, R, R, R, and Reach represent a hydrogen atom or the like, and L represents CH&#x2014;CHor CH&#x2550;CH.

Therapeutic agent for Alzheimer's disease

Growing community of inventors

Kyoto, Japan

Michiaki Okuda