Pioneer Hi-Bred International, Inc.

E.i. Dupont De Nemours and Company

Michi Izumi Willcoxon

Takashi Yamamoto

Yi Zheng

Lu Liu

Eric J Schepers

Ute Schellenberger

Caroline Horn

Sabina Lau

The disclosure provides nucleic acids, and variants and fragments thereof, derived from strains ofencoding variant polypeptides having increased pesticidal activity against insect pests, including Lepidoptera and Coleopteran. Particular embodiments of the disclosure provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.

Insecticidal polypeptides having improved activity spectrum and uses thereof

Insecticidal CRY1B variants having improved activity spectrum and uses thereof

The invention provides nucleic acids, and variants and fragments thereof, obtained from strains ofencoding polypeptides having pesticidal activity against insect pests including, but not limited to, insect pests belonging to the orders Coleoptera and Lepidoptera. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, polynucleotide constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.

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Growing community of inventors

Sunnyvale, CA, United States of America

Michi Izumi Willcoxon