Silk Road Medical, Inc.

Route 92 Medical, Inc.

Heartport, Inc.

Intervene, Inc.

Other

Advanced Cardiovascular Systems, Inc.

Boston Scientific Scimed, Inc.

Cardiovasc, Inc.

Covidien LP

Edwards Lifesciences Corporation

Nfocus Neuromedical, Inc.

Michi E Garrison

Tony M Chou

Gregory M Hyde

Alan K Schaer

Richard Joseph Renati

Scott D Wilson

Enrique Criado

Hanson S Gifford, Iii

Stewart M Kume

John Henry Stevens

Wesley D Sterman

Michael P Wallace

Daniel C Rosenman

Brian S Donlon

Sieu T Duong

Herbert Mendoza

Marlon Moreno

Benjamin J Clark

William S Peters

Fletcher T Wilson

David Batten

Sean Christopher Daniel

S Christopher Daniel

Ronald Hentges

Timothy R Machold

Richard L Mueller

Kent D Dell

Ari Ryan

Herbert M Mendoza

David Mark Taylor

Leon Rudakov

Jan Komtebedde

A Adam Sharkawy

Pinaki Ray

Robert K Deckman

Sumaira Macdonald

Kevin Vincent Grimes

Erica J Rogers

John H Stevens

Leon V Rudakov

Richard M Ruedy

Daniel T Lagoe

Jeffrey M Elkins

Farhad Khosravi

Luke W Clauson

Robert L Lathrop, Jr

Frederick G St Goar

Wiley Alan Kittrell

Gerald R Anderson

David Lari

George Crothall

John L Stevens

Kevin L Ham

Emmanuelle F Pease

James B Mullin

Alan Schaer

Devices and methods are configured to allow transcervical or subclavian access via the common carotid artery to the native aortic valve, and implantation of a prosthetic aortic valve into the heart. The devices and methods also provide means for embolic protection during such an endovascular aortic valve implantation procedure.

Systems and methods for transcatheter aortic valve treatment

According to some embodiments, the present technology includes device for removing obstructive material from a blood vessel lumen. For example, the device can comprise an elongated member, a cutting portion carried by a distal region of the elongated member, and a capture portion carried by the distal region of the elongated member. The cutting portion can comprise a blade configured to separate at least a portion of the obstructive material from the blood vessel wall, and the capture portion can comprise a mesh structure configured to enmesh and/or capture at least a portion of the obstructive material.

Interventional systems and associated devices and methods

An arterial access device has an internal lumen and a proximal port, the arterial access device sized and shaped to be inserted directly into an arterial access site in the common carotid artery such that the lumen provides a passageway for an interventional device to be inserted via the proximal port into the carotid artery. The arterial access device has a distal portion that is configured to be inserted into an arterial pathway through the access site, and a proximal portion configured to extend outward from the access site when the distal portion is in the arterial pathway.

Methods and systems for treatment of acute ischemic stroke

A system of devices for treating an artery includes an arterial access sheath adapted to introduce an interventional catheter into an artery and an elongated dilator positionable within the internal lumen of the sheath body. The system also includes a catheter formed of an elongated catheter body sized and shaped to be introduced via a carotid artery access site into a common carotid artery through the internal lumen of the arterial access sheath. The catheter has an overall length and a distal most section length such that the distal most section can be positioned in an intracranial artery and at least a portion of the proximal most section is positioned in the common carotid artery during use.

An interventional catheter for treating an artery includes an elongated body sized and shaped to be transcervically introduced into a common carotid artery at an access location in the neck. The elongated body has an overall length such that the distal most section can be positioned in an intracranial artery and at least a portion of the proximal most section is positioned in the common carotid artery during use.

Transcarotid neurovascular catheter

The present technology is directed generally to devices, systems, and methods for capturing and cutting fibrous and trabeculated structures (such as synechiae) in vessel lumens. In one embodiment, the present technology includes an intraluminal tissue modifying system configured to capture the fibrous structures, put the fibrous structures in tension, and controllably cut through the fibrous structures without applying appreciable additional force to the vessel wall. The system may include an expandable capture device and a cutting device.

Intraluminal tissue modifying systems and associated devices and methods

Interventional procedures on the carotid arteries are performed through a transcervical access while retrograde blood flow is established from the internal carotid artery to a venous or external location. A system for use in accessing and treating a carotid artery includes an arterial access device, a shunt fluidly connected to the arterial access device, and a flow control assembly coupled to the shunt and adapted to regulate blood flow through the shunt between at least a first blood flow state and at least a second blood flow state. The flow control assembly includes one or more components that interact with the blood flow through the shunt.

Methods and systems for establishing retrograde carotid arterial blood flow

Disclosed is an arterial access sheath for introducing an interventional device into an artery. The arterial access sheath includes an elongated body sized and shaped to be transcervically introduced into a common carotid artery at an access location in the neck and an internal lumen in the elongated body having a proximal opening in a proximal region of the elongated body and a distal opening in a distal region of the elongated body. The internal lumen provides a passageway for introducing an interventional device into the common carotid artery when the elongated body is positioned in the common carotid artery. The elongated body has a proximal section and a distalmost section that is more flexible than the proximal section. A ratio of an entire length of the distalmost section to an overall length of the sheath body is one tenth to one half the overall length of the sheath body.

Methods and devices for transcarotid access

A device is configured for closing an aperture in a wall of a blood vessel. An embodiment of the device includes a body and at least one suture element held within the body. A suture capture rod is positioned within the body and is operatively associated with the suture element and arranged to pass the suture element through a vessel wall such that opposed portions of the suture element extend from the vessel wall. A removable guidewire segment is removably attached to a distal end of the body.

Suture delivery device

Devices and methods are configured to allow transcarotid or subclavian access via the common carotid artery to the native aortic valve, and implantation of a prosthetic aortic valve into the heart. The devices and methods also provide means for embolic protection during such an endovascular aortic valve implantation procedure.

Devices and methods establish and facilitate retrograde or reverse flow blood circulation in the region of the carotid artery bifurcation in order to limit or prevent the release of emboli into the cerebral vasculature such as into the internal carotid artery. The methods are particularly useful for interventional procedures performed through a transcarotid approach or transfemoral into the common carotid artery.

Growing community of inventors

Sunnyvale, CA, United States of America

Michi E Garrison