Abbott Laboratories Corporation

Michelle L Shields

Shelley R Holets-McCormack

Thomas G Spring

Elaine Marie Brate

David M Finley

David P Pacenti

Ryan E Piktel

Phillip P Wang

The present disclosure provides among other things immunoassays exhibiting reduced cross-reactivity with analyte metabolites. Additionally, the present disclosure provides diagnostic immunoassays to determine the concentration or level in a test sample of a hydrophobic drug that metabolizes in vivo or in vitro to form cross-reacting metabolites wherein cross-reactivity with such metabolites of the drug analyte is reduced. In particular, the disclosure provides such immunoassays where the hydrophobic drug is an immunosuppressant drug such as cyclosporine A.

Immunoassays exhibiting reduced cross-reactivity with hydrophobic drug analyte metabolites

Growing community of inventors

Palos Park, IL, United States of America

Michelle L Shields