Wyatt Technology Corporation

Other

Michelle H Chen

Philip J Wyatt

David N Villalpando

Daniel I Some

Sophia Kenrick

The present disclosure describes a computer implemented method, a system, and a computer program product of measuring quality attributes of a virus sample. In an embodiment, the method, system, and computer program product include (1) receiving light scattering (LS) data from a light scattering detector analyzing separations of a virus sample, dRI data, and UV data, (2) receiving a molecular weight of a protein component of the sample, Mprotein (expected), a refractive index increment of the protein component, (dn/dc)protein, a refractive index increment of a DNA component of the sample, (dn/dc)DNA, and an extinction coefficient of the protein component, εprotein, (3) calculating a protein fraction of the sample, xprotein, with respect to the LS data, the dRI data, the Mprotein (expected), the (dn/dc)protein, the (dn/dc)DNA, and an optical constant, K, (4) calculating a DNA extinction coefficient of the sample, εDNA, and (5) calculating quality attribute values of the sample.

Measuring quality attributes of a virus sample

The present disclosure describes a computer implemented method, a system, and a computer program product of calculating molar mass values of components of and molar concentration values of conjugate molecules/particles.

Calculating molar mass values of components of and molar mass concentration values of conjugate molecules/particles

A new type of asymmetric flow field flow fractionator, A4F, is described permitting improved sample fractionation means by providing a range of available channel lengths within the same A4F unit. With such an apparatus, samples may be optimally separated by performing such fractionations as a function of channel length. The ability to vary channel length within the same A4F unit has heretofore been unavailable.

Method and apparatus for optimizing the separation of small particles using the asymmetric flow field flow fractionation method

The present soft article dispenser is comprised of a tube with an open loading end and a constricted dispensing end. The tube is comprised of a rolled up sheet of flexible and collapsible material, such as fabric, with opposite edges which are sewn together. A loading end reinforcing band and a dispensing end reinforcing band are provided at the corresponding ends of the tube. Each reinforcing band is comprised of a rolled up sheet of stronger material, such as leather or vinyl-coated fabric, with opposite edges which are sewn together. The constricted dispensing end is comprised of a disc sewn to the end of the dispensing end reinforcing band. A hole is provided in the disc. A loop is attached to the tube at the open loading end for hanging. Soft articles, such as small items of clothing, plastic bags, disposable gloves, etc., are stuffed snugly into the dispenser from the loading end. The soft articles are removable one-at-a-time through the hole at the dispensing end. When empty, the dispenser is collapsible for compact storage.

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Goleta, CA, United States of America

Michelle H Chen