Adir Et Compagnie

Science Union Et Cie, Societe Francaise De Recherche Medicale

Science Union Et Cie

Les Laboratoires Servier

Les Laboratories Servier

Adir

Adir, S.a.r.l.

Michelle Boulanger

Jacques Duhault

Pierre Hugon

Laszlo Beregi

Gilbert Regnier

Michel Wierzbicki

Alain Dhainaut

Nigel Levens

Francoise Lacour

Bernadette Husson-Robert

Olivier Nosjean

Guillaume De Nanteuil

Alex Cordi

Bernard Portevin

Claude Guillonneau

Jean-Michel Lacoste

Alain Benoist

Joseph Espinal

Jean-Marie Fourquez

Alpha-amino-acid compounds

Cyclic &agr;-amino-&ggr;-hydroxyamide compounds

Compounds of formula (I): ##STR1## in which: R.sub.1 and R.sub.2, which are identical or different, represent a higher alkyl or higher alkenyl radical,

Diacylglycerol nicotinates

The compounds are ethanolamine benzoate compounds useful for the treatment of syndrome X, and of hypertension in patients who are insulin resistant or have one or more metabolic anomalies. A compound disclosed is S-1-(m-trifluoromethylphenyl)-2-{.beta.-{4-[2-(N-(3,3-diphenylpropionyl)am ino)ethyl] benzoyloxy}ethylamino} propane.

Ethanolamine benzoate compounds

New ethanolamine benzoate compounds which can be used as medicaments and correspond to the formula: ##STR1## wherein R is as defined in the description, in the form of racemic compounds and enantiomers. These new compounds and their physiologically tolerable salts can be used therapeutically for treatment of insulin-resistance states.

New xanthine compounds of the formula: ##STR1## in which: R.sub.1 is hydrogen or alkyl from C.sub.1 to C.sub.5 inclusive;

Xanthine compounds

New sulfonylurea compounds of the formula: ##STR1## in which n is 1 or 2,

Sulfonylurea compounds and their use in treating diabetes

Piperidylbenzimidazolinone derivatives of the formula: ##STR1## in which: R.sub.1 is lower alkyl, phenyl, halophenyl, lower alkylphenyl, lower alkoxyphenyl, methylenedioxyphenyl, ethylenedioxyphenyl, thienyl, furyl or pyridyl.

Piperidylbenzimidazolinone derivatives

Piperidylbenzimidazolinone compounds of the formula: ##STR1## in which: R is hydrogen, hydroxy, hydroxymethyl, methoxycarbonyl, formamido, acetamido, mesylamino, oxalamino, ethoxalylamino, carbamoyl ##STR2## ureido ##STR3## or sulfamoylamino ##STR4## in which R' and R' are hydrogen or lower alkyl, T is hydrogen, halogen, lower alkyl or lower alkoxy, and

Piperidylbenzimidazolinone compounds

Pyrrolidone derivatives of the formula: ##STR1## wherein R is hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl, And

Phenoxy phenyl pyrrolidine compounds, compositions and methods of use

Phenoxy compounds of the formula: ##STR1## wherein R and R', which are the same or different, are hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, nitro, trifluoromethyl, trifluoromethylthio, trifluoromethoxy, lower alkoxy-carbonyl or dimethylsulfamoyl. These compounds are used as medicines especially in the treatment of glucid -- and lipid -- metabolism disorders.

N-Phenoxyphenyl-piperazines

Alkanolamine derivatives and their optical isomers of the formula: ##STR1## wherein: N IS 2 OR 3, AND

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Michelle Boulanger